MALIGNANT LYMPHOMA OF THE NASOPHARYNX OF NON-BURKITT'S TYPE

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  • TAKIMOTO TORU
    Department of Otorhinolaryngology, School of Medicine, Kanazawa University
  • MORISHITA KAZUO
    Department of Otorhinolaryngology, School of Medicine, Kanazawa University
  • KAWANAKA TOSHIMASA
    Department of Otorhinolaryngology, School of Medicine, Kanazawa University
  • ISHIKAWA SHIGERU
    Department of Otorhinolaryngology, School of Medicine, Kanazawa University
  • FURUKAWA MITSURU
    Department of Otorhinolaryngology, School of Medicine, Kanazawa University
  • MIYAZAKI TAMEO
    Department of Otorhinolaryngology, School of Medicine, Kanazawa University

Bibliographic Information

Other Title
  • 上いん頭悪性リンパしゅの病因としてＥＢウイルスが考えられた１症例
  • ジョウ イントウ アクセイ リンパシュ ノ ビョウイン ト シテ EB ウイル
  • EBウイルスが考えられた1症例

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Description

A case of EBNA-positive non-Burkitt's lymphoma of the nasopharynx is reported.<br>The patients was 19-year-old female who complained of headache and bilateral cervical lymphoadenopathy for the past one month. Otolaryngological examination revealed a tumor on the lateral and superior wall of the nasopharynx. The tumor was histologically diagnosed as non-Hodgikin's lymphoma (non-Burkitt's type). Serologically, viral capsid antigen and early antigen to Epstein-Barr virus were 640-fold and 40-fold, respectively. EBNA was also detected in the biopsy specimen by anti-complement immunfluorescent test.<br>The patient was treated by irradiation with a dose of 4, 000 rads to the nasopharynx. Also, 4, 000 rads were given to the whole neck, mediastinum and bilateral axillary region. Combination chemotherapy using bleomycin, vincristine, cyclophosphamide and adriamycin was also concurrently performed. She is doing well 3 months after the treatment.

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