{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282680172935680.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2463/mrms.11.185"}},{"identifier":{"@type":"COI","@value":"1:STN:280:DC%2BC3s%2Fis1eitQ%3D%3D"}},{"identifier":{"@type":"PMID","@value":"23037563"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/mrms/11/3/11_185/_pdf"}},{"identifier":{"@type":"NAID","@value":"10031046888"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2013306741"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Diffusion- and T<sub>2</sub>-weighted MR Imaging of the Liver: Effect of Intravenous Administration of Gadoxetic Acid Disodium"},{"@value":"Diffusion- and T2-weighted MR Imaging of the Liver: Effect of Intravenous Administration of Gadoxetic Acid Disodium"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Purpose: We evaluated the effect of intravenous administration of gadoxetic acid disodium to hepatic lesions and liver parenchyma on T<sub>2</sub>-weighted (T<sub>2</sub>WI) and diffusion-weighted imaging (DWI).<br> Materials and Methods: One hundred and one consecutive patients with 259 hepatic lesions underwent T<sub>2</sub>WI and DWI (b-values of 500 and 1000 s/mm<sup>2</sup>) before and after gadoxetic acid administration. We compared the ratio of signal intensity (SIR) of the liver parenchyma and hepatic lesions, the ratio of contrast intensity of the lesion to the liver (CIR), the apparent diffusion coefficients (ADCs) of the liver and lesions, and lesion detectability between pre- and post-contrast images.<br> Results: SIRs, CIRs, and ADC of focal hepatic lesions were comparable on pre- and post-contrast images, and lesion detectability did not differ significantly between pre- and post-contrast T<sub>2</sub>WI and DWI. The SIRs of the liver parenchyma were significantly lower on post-contrast DWI (1.4±0.68 [b=500 s/mm<sup>2</sup>] and 1.71±0.67 [b=1000 s/mm<sup>2</sup>]) than pre-contrast images (1.89±0.68 [b=500 s/mm<sup>2</sup>] and 2.26±0.78 [b=1000 s/mm<sup>2</sup>]) (<i>P</i><0.001). ADCs of the liver parenchyma were also significantly decreased on post-contrast DWI (0.77±0.32 mm<sup>2</sup>/s) than pre-contrast images (0.64±0.33 mm<sup>2</sup>/s) (<i>P</i>=0.001).<br> Conclusion: T<sub>2</sub>WI and DWI after administration of gadoxetic acid are feasible and do not compromise the SIR, CIR, and ADC of focal hepatic lesions. However, the signal intensity of DWI and ADC value of the liver parenchyma were decreased on gadoxetic acid-enhanced hepatocyte phase images.<br>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410282680172935681","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000107311155"}],"foaf:name":[{"@language":"en","@value":"MUHI Ali"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Radiology, University of Yamanashi"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282680172935683","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000107311156"}],"foaf:name":[{"@language":"en","@value":"ICHIKAWA Tomoaki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Radiology, University of Yamanashi"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282680172935682","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000107311157"}],"foaf:name":[{"@language":"en","@value":"MOTOSUGI Utaroh"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Radiology, University of Yamanashi"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282680172935680","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000107311158"}],"foaf:name":[{"@language":"en","@value":"SOU Hironobu"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Radiology, University of Yamanashi"}]},{"@id":"https://cir.nii.ac.jp/crid/1420564276162868736","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"40377578"},{"@type":"NRID","@value":"1000040377578"},{"@type":"NRID","@value":"9000107311159"},{"@type":"NRID","@value":"9000364546503"},{"@type":"NRID","@value":"9000415193642"},{"@type":"NRID","@value":"9000001449679"},{"@type":"NRID","@value":"9000313200602"},{"@type":"NRID","@value":"9000408451788"},{"@type":"NRID","@value":"9000415183311"},{"@type":"NRID","@value":"9000301717833"},{"@type":"NRID","@value":"9000258610406"},{"@type":"NRID","@value":"9000399376871"},{"@type":"NRID","@value":"9000261674109"},{"@type":"NRID","@value":"9000248224806"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0146007"}],"foaf:name":[{"@language":"en","@value":"SANO Katsuhiro"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Radiology, University of Yamanashi"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282680172935684","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000107311160"}],"foaf:name":[{"@language":"en","@value":"ARAKI Tsutomu"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Radiology, University of Yamanashi"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13473182"},{"@type":"LISSN","@value":"13473182"},{"@type":"EISSN","@value":"18802206"},{"@type":"NCID","@value":"AA11648770"}],"prism:publicationName":[{"@language":"en","@value":"Magnetic Resonance in Medical Sciences"},{"@language":"en","@value":"MRMS"},{"@language":"en","@value":"magn reson med sci"}],"dc:publisher":[{"@language":"en","@value":"Japanese Society for Magnetic Resonance in Medicine"},{"@language":"ja","@value":"日本磁気共鳴医学会"}],"prism:publicationDate":"2012","prism:volume":"11","prism:number":"3","prism:startingPage":"185","prism:endingPage":"191"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"https://www.jstage.jst.go.jp/article/mrms/11/3/11_185/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2013306741"}],"availableAt":"2012","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=diffusion-weighted%20MR%20imaging","dc:title":"diffusion-weighted MR imaging"},{"@id":"https://cir.nii.ac.jp/all?q=gadoxetic%20acid","dc:title":"gadoxetic acid"},{"@id":"https://cir.nii.ac.jp/all?q=T%3Csub%3E2%3C/sub%3E-weighted%20MR%20imaging","dc:title":"T<sub>2</sub>-weighted MR imaging"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011143697033856","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Imaging characteristics of hepatocellular carcinoma using the hepatobiliary contrast 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Gd‐EOB‐DTPA and superparamagnetic iron oxide particles in the detection of primary liver cancer: A comparative study by alternative free‐response receiver operating characteristic analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107368910821376","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Enhancement of Focal Liver Lesions at Gadoxetic Acid–enhanced MR Imaging: Correlation with Histopathologic Findings and Spiral CT—Initial Observations"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844839131648","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Liver tumors: comparison of MR imaging with Gd-EOB-DTPA and Gd-DTPA."}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205194551808","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Rules, Roles, and Room for Discussion in Gadoxetic Acid-enhanced Magnetic Resonance Liver 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imaging"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698601106286720","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Liver tumor characterization : comparison between liver-specific gadoxetic acid disodium-enhanced MRI and biphasic CT-a multicenter trial"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698601106506880","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Detection and characterization of focal hepatic tumors : a comparison of T_2-weighted MR images before and after the administration of gadoxectic acid"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698601106508032","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effect of Gd-EOB-DTPA on T_2-weighted and diffusion-weighted images for the diagnosis of hepatocellular 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