{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282680443176192.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3363/prb1992.7.0_1"}},{"identifier":{"@type":"COI","@value":"1:CAS:528:DyaK2sXlt1CltL0%3D"}},{"identifier":{"@type":"NAID","@value":"130004654646"}}],"dc:title":[{"@language":"en","@value":"INHIBITION OF HYDROXYAPATITE CRYSTAL GROWTH BY PHOSPHONATED HYDROXY CARBOXYLIC ACIDS, NON-PHOSPHONATED HYDROXY CARBOXYLIC ACIDS, AND POLY (ACRYLIC ACID)"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"The influence of inhibitors containing various functional groups (i. e., phosphonate, hydroxyl, and carboxyl) on the kinetics of crystal growth of hydroxyapatite (HAP) has been studied at pH=7.40, 37°C and at low supersaturations. It has been found that the crystal growth of HAP is significantly retarded in the presence of micromolar concentrations of hydroxy phosphonoacetic acid (HPA) and 2-phosphono butane 1, 2, 4- tricarboxylic acid (PBTC), with PBTC being a more potent inhibitor than HPA. Three other inhibitors, α-hydroxy carboxylic acids (i. e., glycolic acid, GLA; malic acid, MLA; mandelic acid, MDA), dicarboxylic acid (malonic acid, MNA), and poly (acrylic acid), PAA, all exhibit inhibitory activity but to a varying degree. Among these inhibitors the overall effectiveness, in terms of decreasing power, is PAA>MLA>MNA>GLA>MDA. The retarding effect of these inhibitors is discussed in relation to the calcium-inhibitor complex formation on the HAP seed crystals and the structural features of the inhibitor molecules. The fit of the experimental data to the Langmuir adsorption isotherm supports a mechanism of inhibition through molecular adsorption of the inhibitor ions on the surface of the growing crystals."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410282680443176192","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258633220"}],"foaf:name":[{"@language":"en","@value":"AMJAD ZAHID"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The BFGoodrich Company, Advanced Technology Group"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09184783"}],"prism:publicationName":[{"@language":"en","@value":"Phosphorus Research Bulletin"},{"@value":"Phosphorus Research Bulletin"},{"@language":"en","@value":"Phosphorus Research Bulletin"},{"@value":"Phosphorus Research Bulletin"}],"dc:publisher":[{"@language":"en","@value":"Japanese Association of Inorganic Phosphorus Chemistry"}],"prism:publicationDate":"1997","prism:volume":"7","prism:number":"0","prism:startingPage":"1","prism:endingPage":"15"},"reviewed":"false","availableAt":"1997","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360292619265421824","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Inhibition of hydroxyapatite formation in aqueous solutions by zinc and 1,2-dihydroxy-1,2-bis(dihydroxyphosphonyl)ethane"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574094623884672","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The influence of polyphosphates, phosphonates, and poly(carboxylic acids) on the crystal growth of hydroxyapatite"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044534506496","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Structural factors influencing the ability of compounds to inhibit hydroxyapatite formation"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045829405568","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The crystallization of hydroxyapatite and fluorapatite in the presence of magnesium ions"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418521517331968","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mineral Scale Formation and Inhibition"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993414640896","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The influence of phytate and phosphonate on the crystal growth of fluorapatite and hydroxyapatite"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994434259584","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Inhibition of the amorphous calcium phosphate phase transformation reaction by polyphosphates and metal ions"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995012738176","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The inhibition of dicalcium phosphate dihydrate crystal growth by polycarboxylic acids"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469504291712","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Effect of precipitation inhibitors on calcium phosphate scale formation"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544419574285568","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Crystal growth of calcium phosphates in the presence of magnesium ions"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895837387648","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Adsorption and mineralization effects of citrate and phosphocitrate on hydroxyapatite"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270318239744","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Étude thermodynamique du mélange chlore – acide isocyanurique en milieu aqueux"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233271235646592","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Effect of magnesium on formation of calcium phosphate precipitates"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680443232384","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"PERFORMANCE OF POLYMERIC ADDITIVES AS HYDROXYAPATITE CRYSTAL GROWTH INHIBITORS"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:1001625488"},{"@type":"CROSSREF","@value":"10.3363/prb1992.7.0_1"},{"@type":"CIA","@value":"130004654646"}]}