Antihypertensive Effect of Water Extracts from Leaves of Moringa oleifera Lam. on Spontaneously Hypertensive Rats

DOI 18 References
  • Kajihara Ryo
    Hiroshima Prefectural Technology Research Institute Food Technology Research Center
  • Nakatsu Sayaka
    Hiroshima Prefectural Technology Research Institute Food Technology Research Center
  • Shiono Tadahiko
    Hiroshima Prefectural Technology Research Institute Food Technology Research Center
  • Shibata Kenya
    Hiroshima Prefectural Technology Research Institute Food Technology Research Center
  • Ishihara Masako
    Hiroshima Prefectural Technology Research Institute Food Technology Research Center
  • Sakamoto Koji
    Hiroshima Prefectural Technology Research Institute Food Technology Research Center
  • Muto Norio
    School of Faculty of Life and Environmental Sciences, Hiroshima Prefectural University

Bibliographic Information

Other Title
  • 高血圧自然発症ラットにおけるモリンガ葉水抽出物の抗高血圧作用
  • コウケツアツ シゼン ハッショウ ラット ニ オケル モリンガ ヨウスイ チュウシュツブツ ノ コウコウケツアツ サヨウ

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Abstract

The antihypertensive effect of water extracts from leaves of Moringa oleifera Lam. was studied in spontaneously hypertensive rats (SHR). Extracts (10g of the dried leaves with 100ml of water) were given to SHR by a single oral administration at 3ml/kg body weight or by repeated oral administrations at 3ml/kg body weight/day for 6 weeks. The water extracts contained 0.3mg/ml of γ-aminobutyric acid (GABA). Although the single oral administration of the water extract could not reduce systolic blood pressure in SHR, repeated oral administration for 6 weeks resulted in significant decreases compared with the control. These results suggest that the daily intake of Moringa oleifera Lam. was effective for prevention against hypertension.

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Details

  • CRID
    1390282681385860224
  • NII Article ID
    10021178595
  • NII Book ID
    AN10467499
  • DOI
    10.3136/nskkk.55.183
  • ISSN
    18816681
    1341027X
  • NDL BIB ID
    9455678
  • Text Lang
    ja
  • Data Source
    • JaLC
    • NDL
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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