CLINICAL FEATURES AND ENDOSCOPIC FINDINGS OF AUTOIMMUNE GASTRITIS AND RESULTANT GASTRIC TUMOR
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- KAMADA Tomoari
- Department of Health Care Medicine, Kawasaki Medical School. General Health Promotion Center, Kawasaki Medical School General Medical Center.
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- MONOBE Yasumasa
- Department of Pathology, Kawasaki Medical School.
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- HARUMA Ken
- Department of General Internal Medicine 2, Kawasaki Medical School.
Bibliographic Information
- Other Title
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- 自己免疫性胃炎および合併胃腫瘍の臨床像と内視鏡所見
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Description
<p>Autoimmune gastritis (AIG) is a special type of gastritis in which parietal cells are destroyed due to autoimmune abnormalities such as anti-parietal cell antibodies that are produced against the proton pump (H+/K+ ATPase) in the process. AIG is characterized by reverse atrophy on endoscopy. In addition, findings such as sticky adherent dense mucus, remnant oxyntic mucosa, and circular wrinkle-like patterns in the antrum can be observed. Endoscopic images of early-stage AIG obtained from recent reports have shown features such as longitudinal reddish pseudopolyp-like nodules, thickened and edematous mucosa, and mosaic-like patterns of the pits on the greater curvature of the corpus.</p><p>Gastric cancer complicated with AIG is an early intestinal cancer that is located mainly in the L to M region. The serum gastrin level and prevalence of pernicious anemia were higher in gastric cancer cases complicated with AIG than in non-gastric cancer AIG cases. Furthermore, histological analysis of the background gastric mucosa in gastric cancer cases complicated with AIG revealed severe atrophy and mild mononuclear infiltration compared with non-gastric cancer AIG cases.</p><p>Gastric neuroendocrine tumors complicated with AIG were classified as type I by Rindi et al. These tumors, located in the corpus, have a small diameter and are accompanied by hypergastrinemia. They have a good clinical prognosis. The predominant colors in the tumor are pale yellow and red. Dilated vessels, redness, and depressions may be observed in the center of the tumor.</p>
Journal
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- GASTROENTEROLOGICAL ENDOSCOPY
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GASTROENTEROLOGICAL ENDOSCOPY 63 (8), 1520-1537, 2021
Japan Gastroenterological Endoscopy Society
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Details 詳細情報について
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- CRID
- 1390289099789246592
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- NII Article ID
- 130008076297
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- ISSN
- 18845738
- 03871207
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed