A skin biopsy case of Mpox virous infection

DOI
  • Tasaki Takashi
    Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences
  • Baba Naoko
    Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences
  • Noguchi Hiroyuki
    Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences
  • Murakami Miki
    Department of Pathology, Kagoshima University Hospital
  • Kitazono Ikumi
    Department of Pathology, Kagoshima University Hospital
  • Higashi Michiyo
    Department of Pathology, Kagoshima University Hospital
  • Tanimoto Akihide
    Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences Department of Pathology, Kagoshima University Hospital

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Other Title
  • 典型的な皮膚病変を呈したMpoxの1症例

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<p>We report a case of Mpox virus infection in 30s-year-old man.　He had sexual contact with a multiple sex partner one month ago.　He had a fever and skin rash （erythema, papules or pseudopustules） on his chest, forearms, palms, and penis.　Microscopic examination of the skin biopsied specimen from his chest revealed epidermal necrosis with shadow cells, balloon cell degeneration, and exocytosis of neutrophils.　Eosinophilic inclusion bodies were observed in keratinocytes.　A final diagnosis of Mpox virus infection was confirmed by PCR.　As the histopathological features are not specific for Mpox virus infection, it is necessary to interactively diagnose in combination with patient’s history and clinical findings.</p>

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