A Case of an Enterocutaneous Fistula Caused by Sodium Hyaluronate Carboxymethylcellulose Bioresorbable Membrane-induced Intestinal Adhesions

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  • Nagata Yuki
    Departments of Cardiovascular and Gastroenterological Surgery, Kagoshima University Graduate School of Medical and Dental Sciences
  • Kadono Jun
    Departments of Cardiovascular and Gastroenterological Surgery, Kagoshima University Graduate School of Medical and Dental Sciences
  • Motoi Shunsuke
    Departments of Cardiovascular and Gastroenterological Surgery, Kagoshima University Graduate School of Medical and Dental Sciences
  • Tasaki Takashi
    Department of Human Pathology, Field of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences
  • Imoto Yutaka
    Departments of Cardiovascular and Gastroenterological Surgery, Kagoshima University Graduate School of Medical and Dental Sciences

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  • セプラフィルム<sup>®</sup>が誘発したと考えられた癒着による腸管皮膚瘻の1例

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Abstract

<p>【Background】A sodium hyaluronate carboxymethylcellulose bioresorbable membrane (Seprafilm®) is used frequently to prevent postoperative adhesions. It has been considered as an efficient and a safe tool. We report herein on a case of an enterocutaneous fistula caused by Seprafilm®-induced intestinal adhesions. 【Case presentation】A 79-year-old male was admitted to our department with an enterocutaneous fistula 42 days after the graft replacement for an abdominal aortic aneurysm. Seprafilm® had been placed at the time of the previous operation. A repeat laparotomy demonstrated dense adhesions between the small intestine and the abdominal wall. The enterocutaneous fistula and the adhered intestine were resected en-bloc. The pathological examination of the resected small intestine showed diffuse subserosal fibrosis with multinuclear giant cells containing a clear foreign body. It was suggested that a paradoxical inflammatory reaction to Seprafilm® caused the dense adhesions.【Conclusion】It should be kept in mind that Seprafilm® may also cause dense adhesions.</p>

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