Factors associated with symptoms of depression among pregnant women with gestational diabetes mellitus in Japan

  • Hayashi Ayako
    Department of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Oguchi Hidenori
    Department of Obstetrics and Gynecology, TOYOTA Memorial Hospital, Toyota, Japan.
  • Kozawa Yumi
    Division of Endocrinology and Nutrition, TOYOTA Memorial Hospital, Toyota, Japan.
  • Ban Yukiko
    Division of Endocrinology and Nutrition, TOYOTA Memorial Hospital, Toyota, Japan.
  • Shinoda Junji
    Division of Endocrinology and Nutrition, TOYOTA Memorial Hospital, Toyota, Japan.
  • Suganuma Nobuhiko
    Department of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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Description

<p>The objective of this study was to explore the factors associated symptoms of depression among pregnant women with gestational diabetes mellitus (GDM) in Japan. This cross-sectional study was conducted at a hospital in Toyota, Japan, from January 2015 to June 2016. Pregnant women who visited the hospital and were diagnosed with GDM in the second trimester were enrolled. We analyzed depression symptoms using the Centers for Epidemiological Studies Depression Scale (CES-D) and considered related factors of depression symptoms, such as dietary intake and daily walking. Dietary intake during the past month was assessed using a brief self-administered diet history questionnaire, and daily walking was assessed using an accelerometer. The prevalence rate for GDM was 8.8%, and 25 pregnant women with GDM were analyzed. The CES-D was not significantly correlated with pre-pregnancy BMI, postprandial plasma glucose, hemoglobin A1c, and the number of steps walked. In contrast, a significant negative correlation was observed between the CES-D score and intake of fish with bones, simmered fish, pickles, green leaves, mushrooms, and green tea. Furthermore, a significant positive correlation was found between Coke® and CES-D scores. For nutrient intake, a significant negative correlation was found between the CES-D score and vitamin K, folate, and β-carotene levels. The present study suggests that depression symptoms among pregnant women with GDM in the second trimester may be associated with diet.</p>

Journal

  • Drug Discoveries & Therapeutics

    Drug Discoveries & Therapeutics 14 (5), 232-238, 2020-10-31

    International Research and Cooperation Association for Bio & Socio-Sciences Advancement

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