A case of isolated right ventricle metastasis of hepatocellular carcinoma treated with lenvatinib

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  • Minamikawa Yoko
    Department of Internal Medicine, Japan Community Health care Organization Kyushu Hospital
  • Ichiki Yasunori
    Department of Internal Medicine, Japan Community Health care Organization Kyushu Hospital
  • Kamihira Takashi
    Department of Internal Medicine, Japan Community Health care Organization Kyushu Hospital
  • Mizue Ryutaro
    Department of Internal Medicine, Japan Community Health care Organization Kyushu Hospital
  • Wachi Hiroshi
    Department of Internal Medicine, Japan Community Health care Organization Kyushu Hospital
  • Hirata Takashi
    Department of Internal Medicine, Japan Community Health care Organization Kyushu Hospital
  • Nagata Yutaka
    Department of Internal Medicine, Japan Community Health care Organization Kyushu Hospital
  • Hashimoto Satoru
    Department of Internal Medicine, Japan Community Health care Organization Kyushu Hospital
  • Shimoda Shinji
    Department of Infection Disease Internal Medicine, Karatsu Red Cross Hospital

Bibliographic Information

Other Title
  • 右心室に転移した肝細胞癌に対しレンバチニブを投与した一例
  • ウシンシツ ニ テンイ シタ カン サイボウ ガン ニ タイシ レンバチニブ オ トウヨ シタ イチレイ

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Description

<p>An 82-year-old male underwent extended left hepatectomy for hepatocellular carcinoma (HCC) 3 years ago. Then, the patient was performed transarterial chemoembolization for multiple intrahepatic recurrences 2 years ago, and percutaneous radiofrequency ablation for another solitary recurrence a year ago. In October 2019, the patient was diagnosed with right ventricular metastasis without inferior vena cava or right atrial invasion. Four and eight weeks after the administration of lenvatinib, the right ventricular tumor appeared to shrink and was evaluated as stable disease according to the Response Evaluation Criteria in Solid Tumors, version 1.1. Lenvatinib was continued for 12 months and changed to regorafenib because of proteinuria and the gradually enlarging right ventricular tumor. The patient is still alive 14 months after the diagnosis of cardiac metastasis. Here we report a rare case of isolated cardiac metastasis of HCC treated with lenvatinib.</p>

Journal

  • Kanzo

    Kanzo 62 (8), 494-500, 2021-08-01

    The Japan Society of Hepatology

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