Five Cases of Xanthogranulomatous Sialadenitis

Kiyama Satoshi, Iuchi Hiroyuki, Ito Kotoko, Nishimoto Kengo, Matsuzaki Tsutomu, Yamashita Masaru

doi:10.5631/jibirin.115.315

<p>Xanthogranulomatous tissue reaction, which is frequently mistaken for malignant tumor, is known to occur at many sites in the body, but is rarely seen in the salivary glands. Only 11 cases of xanthogranulomatous sialadenitis (XGS) have been reported in the literature. Herein, we report five cases of XGS and summarize the clinical features of these cases and also previously reported cases. Pain, which is the most common complication, was recorded in 11 cases. In general, benign parotid tumors are rarely painful, so we believe that the high frequency of pain in cases of XGS is one of the factors that make it difficult to distinguish it from malignant tumors. The onset site was the parotid gland in 14 cases, the submandibular gland in 1 case, and the sublingual gland in 1 case. No identifiable tumor was observed in 10 cases. Warthin’s tumor was identified in 5 cases, and mucoepidermoid carcinoma in 1 case. The most case of XGS, which was without malignant tumor, presented with facial nerve paralysis. Since it is difficult to confirm the diagnosis of XGS before surgery, rapid intraoperative diagnosis may allow appropriate and timely treatment to be undertaken. Pain, absence of malignant findings on FNA, and focal lesions with rim enhancement on dynamic magnetic resonance imaging may aid in the diagnosis.</p>

Five Cases of Xanthogranulomatous Sialadenitis

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