{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390573560406757888.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.5631/jibirinsuppl.158.163"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"031985490"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/031985490"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I031985490"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/jibirinsuppl/158/0/158_163/_pdf"}},{"identifier":{"@type":"NAID","@value":"40022823359"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2022163925"}}],"dc:title":[{"@language":"en","@value":"Clinical Outcomes of Treatment for Hypopharyngeal Cancer at Tokushima University Hospital"},{"@language":"ja","@value":"当科における下咽頭癌の治療成績"},{"@language":"ja-Kana","@value":"トウ カ ニ オケル カイントウ ガン ノ チリョウ セイセキ"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<p>In the present retrospective study, a total of 44 patients with hypopharyngeal cancer who had received their primary treatment at the Department of Otolaryngology Head and Neck Surgery, Tokushima University Hospital, between July 2010 and June 2015 were enrolled. The five-year overall survival and disease-specific survival (DSS) rates were 53% and 65%, respectively. In the 41 patients who underwent radical treatment (median follow-up period: 64 months), the T status was identified as an independent predictor of the DSS and distant metastasis-free survival (DMFS) rates, and the N status was found to be an independent predictor of the DSS, regional control, and DMFS rates. The five-year DMFS rate in the patients with T3 or T4 disease who had undergone total pharyngolaryngectomy (TPL) after induction chemotherapy (ICT) was significantly higher (67%) than that in the patients who had undergone TPL alone (33%). This finding suggests that ICT may suppress distant metastasis in patients with advanced, but resectable, hypopharyngeal cancer.</p>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410573560406757888","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415416352"}],"foaf:name":[{"@language":"en","@value":"Ishitani Keisuke"},{"@language":"ja","@value":"石谷 圭佑"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Tokushima University Hospital"},{"@language":"ja","@value":"徳島大学病院耳鼻咽喉科・頭頸部外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410573560406757889","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000412377489"}],"foaf:name":[{"@language":"en","@value":"Fujino Katsuya"},{"@language":"ja","@value":"藤野 勝也"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Tokushima University Hospital"},{"@language":"ja","@value":"徳島大学病院耳鼻咽喉科・頭頸部外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410573560406757891","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000347674253"}],"foaf:name":[{"@language":"en","@value":"Naito Keisuke"},{"@language":"ja","@value":"内藤 圭介"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"徳島大学病院耳鼻咽喉科・頭頸部外科"},{"@language":"en","@value":"Tokushima University Hospital"}]},{"@id":"https://cir.nii.ac.jp/crid/1410573560406757893","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415416355"}],"foaf:name":[{"@language":"en","@value":"Kondo Eiji"},{"@language":"ja","@value":"近藤 英司"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"徳島大学病院耳鼻咽喉科・頭頸部外科"},{"@language":"en","@value":"Tokushima University Hospital"}]},{"@id":"https://cir.nii.ac.jp/crid/1410573560406757890","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415416356"}],"foaf:name":[{"@language":"en","@value":"Abe Koji"},{"@language":"ja","@value":"阿部 晃治"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"徳島赤十字病院耳鼻咽喉科"},{"@language":"en","@value":"Tokushima Red Cross Hospital"}]},{"@id":"https://cir.nii.ac.jp/crid/1410573560406757894","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415416357"}],"foaf:name":[{"@language":"en","@value":"Tamura Koichi"},{"@language":"ja","@value":"田村 公一"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"徳島市民病院耳鼻咽喉科"},{"@language":"en","@value":"Tokushima Municipal Hospital"}]},{"@id":"https://cir.nii.ac.jp/crid/1410573560406757892","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415416358"}],"foaf:name":[{"@language":"en","@value":"Kitamura Yoshiaki"},{"@language":"ja","@value":"北村 嘉章"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Tokushima University Hospital"},{"@language":"ja","@value":"徳島大学病院耳鼻咽喉科・頭頸部外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410573560406757895","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415416359"}],"foaf:name":[{"@language":"en","@value":"Takeda Noriaki"},{"@language":"ja","@value":"武田 憲昭"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"徳島大学病院耳鼻咽喉科・頭頸部外科"},{"@language":"en","@value":"Tokushima University Hospital"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09121870"},{"@type":"EISSN","@value":"21851557"},{"@type":"NDL_BIB_ID","@value":"000000043681"},{"@type":"ISSN","@value":"09121870"},{"@type":"LISSN","@value":"09121870"},{"@type":"NCID","@value":"AN10020883"}],"prism:publicationName":[{"@language":"en","@value":"Practica oto-rhino-laryngologica. Suppl."},{"@language":"ja","@value":"耳鼻咽喉科臨床　補冊"},{"@language":"en","@value":"Pract.Otol.(Kyoto)"},{"@language":"en","@value":"Jibi inkoka rinsho"},{"@language":"ja","@value":"耳鼻臨床"}],"dc:publisher":[{"@language":"en","@value":"The Society of Practical Otolaryngology"},{"@language":"ja","@value":"耳鼻咽喉科臨床学会"}],"prism:publicationDate":"2022","prism:volume":"158","prism:number":"0","prism:startingPage":"163","prism:endingPage":"170"},"reviewed":"false","url":[{"@id":"http://id.ndl.go.jp/bib/031985490"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I031985490"},{"@id":"https://www.jstage.jst.go.jp/article/jibirinsuppl/158/0/158_163/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2022163925"}],"availableAt":"2022","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=hypopharyngeal%20cancer","dc:title":"hypopharyngeal cancer"},{"@id":"https://cir.nii.ac.jp/all?q=squamous%20cell%20carcinoma","dc:title":"squamous cell carcinoma"},{"@id":"https://cir.nii.ac.jp/all?q=survival%20rate","dc:title":"survival rate"},{"@id":"https://cir.nii.ac.jp/all?q=induction%20chemotherapy","dc:title":"induction chemotherapy"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011144594051456","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Randomized Phase III Trial to Test Accelerated Versus Standard Fractionation in Combination With Concurrent Cisplatin for Head and Neck Carcinomas in the Radiation Therapy Oncology Group 0129 Trial: Long-Term Report of Efficacy and Toxicity"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011145439094656","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cisplatin and Fluorouracil Alone or with Docetaxel in Head and Neck Cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095802231168","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Prophylactic Swallow Therapy for Patients with Head and Neck Cancer Undergoing Chemoradiotherapy: A Randomized Trial"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569264944896","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Induction chemotherapy decreases the rate of distant metastasis in patients with head and neck squamous cell carcinoma but does not improve survival or locoregional control: A meta-analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699995218437888","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Feasibility Study of Single Agent Cisplatin and Concurrent Radiotherapy in Japanese Patients with Squamous Cell Carcinoma of the Head and Neck: Preliminary Results"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544419126634624","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893528502528","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Total Pharyngolaryngectomy for Squamous Cell Carcinoma of the Hypopharynx: A Review"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369053847552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Long-Term Results of a Multicenter Randomized Phase III Trial of Induction Chemotherapy With Cisplatin, 5-fluorouracil, ± Docetaxel for Larynx Preservation"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205015149824","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"下咽頭癌の生存率の変化"},{"@language":"en","@value":"Trends in the Detail of the Stage and Survival Rate in Hypopharyngeal Cancer over 20 Years"},{"@value":"下咽頭癌の生存率の変化 : 過去20年間4期の比較"},{"@language":"ja-Kana","@value":"カイントウ ガン ノ セイゾンリツ ノ ヘンカ : カコ 20ネンカン 4キ ノ ヒカク"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:2009335336"},{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R000000004-I031985490"},{"@type":"CROSSREF","@value":"10.5631/jibirinsuppl.158.163"},{"@type":"CIA","@value":"40022823359"},{"@type":"OPENAIRE","@value":"doi_________::d8f82c39a4edd402d31e50b45c4e8627"}]}