Predictors of Improvement in Exercise Capacity After Cardiac Rehabilitation Differ Between Octogenarian and Young-Old Patients With Acute Myocardial Infarction

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  • Noguchi Teruo
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Yasuda Satoshi
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Nakanishi Michio
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Goto Yoichi
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center Yoka Municipal Hospital
  • Tokeshi Tatsuo
    Department of Cardiac Rehabilitation, National Cerebral and Cardiovascular Center Shonan Hospital
  • Date Ayumi
    Department of Cardiac Rehabilitation, National Cerebral and Cardiovascular Center
  • Miura Hiroyuki
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Kumasaka Leon
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Arakawa Tetsuo
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Nakao Kazuhiro
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Fukui Shigefumi
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Hasegawa Takuya
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Yanase Masanobu
    Department of Transplantation, National Cerebral and Cardiovascular Center

Bibliographic Information

Published
2023-05-25
Resource Type
journal article
DOI
  • 10.1253/circj.cj-22-0606
Publisher
The Japanese Circulation Society

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Description

<p>Background: Whether the magnitude and predictors of improvement in exercise capacity after cardiac rehabilitation (CR) are the same between young-old (YO) and octogenarian (OCT) patients with acute myocardial infarction (AMI) is unknown.</p><p>Methods and Results: We studied 284 YO (age range 65–69 years; mean [±SD] 67±1 years) and 65 OCT (age range ≥80 years; mean [±SD] 83±2 years) patients who participated in a post-AMI CR program. After 3 months of CR, peak oxygen uptake (PV̇O2) measured during cardiopulmonary exercise testing improved significantly in both age groups (P<0.01), although the percentage increase in PV̇O2(%∆PV̇O2) was significantly smaller in the OCT than YO group (5.4±13.7% vs. 10.0±12.8%; P<0.01). Multiple regression analysis demonstrated that independent predictors of %∆PV̇O2were the number of outpatient CR (OPCR) sessions attended (P=0.015), left ventricular ejection fraction (P=0.028), and baseline PV̇O2(P=0.0007) in the YO group; and the number of sessions attended (P=0.018), atrial fibrillation (P=0.042), and the presence of nutritional risk (Geriatric Nutritional Risk Index ≤98; P=0.036) in the OCT group.</p><p>Conclusions: The predictors of improvement in exercise capacity after CR differed between the YO and OCT patients with AMI. To obtain a greater improvement in PV̇O2in CR, frequent OPCR session attendance may be necessary in both groups; in addition, particularly in OCT patients, better nutritional status may be important.</p>

Journal

  • Circulation Journal

    Circulation Journal 87 (6), 815-823, 2023-05-25

    The Japanese Circulation Society

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