Malignant Solitary Fibrous Tumour of the Visceral Pleura—Report of a Case—

Bibliographic Information

Other Title
  • 臓側胸膜由来悪性孤立性線維性腫瘍の1例
  • ゾウソクキョウマク ユライ アクセイ コリツセイ センイセイ シュヨウ ノ 1レイ
Published
2023
DOI
  • 10.3919/jjsa.84.1032
Publisher
Japan Surgical Association

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Description

<p>A 57-year-old woman presented to our hospital with dyspnea and chest pain of which she had been aware. A chest CT scan revealed an 18 × 13 cm chest wall tumor in the right thoracic cavity. CT-guided percutaneous needle biopsy led to a diagnosis of solitary fibrous tumor (SFT). It was difficult to differentiate whether the tumor was benign or malignant based on CT, MRI and FDG-PET findings. In December 2020, we performed thoracoscopic-assisted tumor excision. The histopathological study revealed patternless proliferation of spindle-shaped cells. The mitotic figure was 16/10HPF. Immunostaining studies showed CD34 positive and STAT6 positive. From these findings, we diagnosed the case as high-risk malignant SFT. The surgical stump was negative, indicating that a surgical complete resection could be achieved. No adjuvant chemotherapy was added, and the patient has been followed without any therapies.</p><p>Malignant SFT is an extremely rare entity, and its diagnostic criteria are still obscure. However, the risk of recurrence has been described in a variety of reports. We here present a case of SFT which was diagnosed as malignant and treated by surgical resection, with literature review.</p>

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