咽頭表在癌に対する超音波内視鏡検査による Tumor thickness 評価の有用性の検討 : パイロット研究
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- 前田 英仁
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 佐々木 文郷
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 樺山 雅之
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 岩屋 博道
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 小牧 祐雅
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 有馬 志穂
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 田ノ上 史郎
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 橋元 慎一
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 上村 修司
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 宮下 圭一
- Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 大堀 純一郎
- Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 山下 勝
- Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University
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- 井戸 章雄
- Digestive and Lifestyle Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University
書誌事項
- タイトル別名
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- Efficacy of endoscopic ultrasonography in evaluating tumor thickness in patients with superficial pharyngeal carcinoma: A pilot study
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説明
A histopathological tumor thickness of ≥1000 μm has been reported as one of many risk factors for recurrent lymph node metastasis in superficial pharyngeal cancer (SPC). However, methods for assessing this risk factor preoperatively have not yet been established. Hence, the current study aimed to evaluate the efficacy of endoscopic ultrasonography (EUS) in measuring tumor thickness preoperatively in patients with SPC.This single-center retrospective study included 44 consecutive patients with 47 lesions who underwent endoscopic submucosal dissection (ESD). Prior to surgery, EUS examination was performed while under general anesthesia. Further, microvascular irregularity in the target lesion was evaluated using the Japan Esophageal Society (JES) magnification endoscopic classification system.A significant correlation was noted between histopathological and EUS tumor thickness (Spearman's correlation r == 0.879, p 0.001). In tumors ≥1000 µm thick on histopathology, the cutoff value for EUS tumor thickness was 2.6 mm, and the following values were obtained: sensitivity, 100%; specificity, 81.8%; positive predictive value (PPV), 70%; negative predictive value (NPV), 100%; and accuracy, 87.2%. In B2 lesions ≥1000-μm thick, the following values were obtained: sensitivity, 85.7%; specificity, 90.9%; PPV, 80%; NPV, 93.8%; and accuracy, 89.4%. The diagnostic accuracy rate of combined EUS and the JES magnifying endoscopic classification system was 95.7%.Tumor thickness assessed using EUS was effective in diagnosing histopathological tumor thickness of ≥1000 μm. The combined use of EUS and the JES magnifying endoscopic classification system may be useful for assessing preoperative risk factors for lymph node metastasis in SPC.
収録刊行物
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- 日本耳鼻咽喉科頭頸部外科学会会報
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日本耳鼻咽喉科頭頸部外科学会会報 127 (1), 54-56, 2024-01-20
一般社団法人 日本耳鼻咽喉科頭頸部外科学会