{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390583812015582592.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.11386/jst.59.2_119"}}],"dc:title":[{"@language":"en","@value":"The Indications for Liver Transplantation in Recipients with pre-transplant or Coexisting Malignancies"},{"@language":"ja","@value":"悪性腫瘍の既往・併存レシピエントに対する肝移植の適応"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<p>The increase in liver transplant (LT) recipients’ age and improved survival rates have led to more patients with pre-transplant malignancies (PTMs). Common risk factors, like obesity and alcohol use, often link nonhepatic cancer with chronic liver diseases. Immunosuppressive therapy in LT recipients raises the risk of post-transplant cancer recurrence, affecting survival rates. Although PTM’s impact is well-studied in kidney transplants, data for LT is limited. Patients with cirrhosis and cancer have outcomes influenced by cirrhosis severity and chemotherapy’s impact on liver function. This study examines LT eligibility and required waiting period for PTM patients, focusing on cancer type and treatment history. Comprehensive cancer history is essential for evaluating LT eligibility. Future research should gather extensive data on PTM’s effect on post-LT outcomes, identifying recurrence risk factors to improve management and survival.</p>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410583812015582593","@type":"Researcher","foaf:name":[{"@language":"en","@value":"TOSHIMA Takeo"},{"@language":"ja","@value":"戸島 剛男"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"九州大学　消化器・総合外科"},{"@language":"en","@value":"Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410583812015582594","@type":"Researcher","foaf:name":[{"@language":"en","@value":"ITOH Shinji"},{"@language":"ja","@value":"伊藤 心二"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"九州大学　消化器・総合外科"},{"@language":"en","@value":"Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410583812015582592","@type":"Researcher","foaf:name":[{"@language":"en","@value":"YOSHIZUMI Tomoharu"},{"@language":"ja","@value":"吉住 朋晴"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"九州大学　消化器・総合外科"},{"@language":"en","@value":"Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"05787947"},{"@type":"EISSN","@value":"21880034"}],"prism:publicationName":[{"@language":"en","@value":"Japanese Journal of Transplantation"},{"@language":"ja","@value":"移植"},{"@language":"en","@value":"Japanese Journal of Transplantation"},{"@language":"ja","@value":"移植"}],"dc:publisher":[{"@language":"en","@value":"The Japan Society for Transplantation"},{"@language":"ja","@value":"一般社団法人 日本移植学会"}],"prism:publicationDate":"2024","prism:volume":"59","prism:number":"2","prism:startingPage":"119","prism:endingPage":"128"},"availableAt":"2024","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=pre-transplant%20malignancy","dc:title":"pre-transplant malignancy"},{"@id":"https://cir.nii.ac.jp/all?q=liver%20transplantation","dc:title":"liver transplantation"},{"@id":"https://cir.nii.ac.jp/all?q=malignant%20tumor","dc:title":"malignant tumor"},{"@id":"https://cir.nii.ac.jp/all?q=de%20novo%20malignancy","dc:title":"de novo malignancy"},{"@id":"https://cir.nii.ac.jp/all?q=immunosuppressant","dc:title":"immunosuppressant"},{"@id":"https://cir.nii.ac.jp/all?q=pre-transplant%20malignancy","dc:title":"pre-transplant malignancy"},{"@id":"https://cir.nii.ac.jp/all?q=liver%20transplantation","dc:title":"liver transplantation"},{"@id":"https://cir.nii.ac.jp/all?q=malignant%20tumor","dc:title":"malignant tumor"},{"@id":"https://cir.nii.ac.jp/all?q=de%20novo%20malignancy","dc:title":"de novo malignancy"},{"@id":"https://cir.nii.ac.jp/all?q=immunosuppressant","dc:title":"immunosuppressant"}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:2013556743"}]}