A case of pleomorphic adenoma with tyrosine rich crystalloids

DOI
  • Tasaki Takashi
    Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences
  • Noguchi Hiroyuki
    Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences
  • Murakami Miki
    Department of Pathology, Kagoshima University Hospital
  • Kitazono Ikumi
    Department of Pathology, Kagoshima University Hospital
  • Higashi Michiyo
    Department of Pathology, Kagoshima University Hospital
  • Tanimoto Akihide
    Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences Department of Pathology, Kagoshima University Hospital

Bibliographic Information

Other Title
  • Tyrosine-rich crystalloidsを伴う多形腺腫の1例
Published
2025
DOI
  • 10.69281/jspjjdp.2025_01_0003
Publisher
The Japanese Society of Pathology

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Description

<p>Pleomorphic adenoma is the most common salivary gland tumor.　Tyrosine-rich crystalloids （TRCs） are rarely seen in the chondromyxoid stromal component of this tumor.　We report a case of pleomorphic adenoma with TRCs in 70s-year-old woman.　The tumor was 65 mm in diameter and located in the right parotid gland.　Microscopic examination revealed numerous floret-like TRCs in abundant myxoid stroma and myoepithelial nests.　TRCs were more clearly observed by Giemsa stain.　TRCs are most frequently seen in pleomorphic adenoma, however, they are also known to be seen in other salivary gland tumors, including malignant tumors, and non-neoplastic tissues.　TRCs should not be a diagnostic clue for pleomorphic adenoma.</p>

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