{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390588369390010752.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2169/internalmedicine.6455-25"}},{"identifier":{"@type":"PMID","@value":"41535031"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_6455-25/_pdf"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Podocytic Infolding Gromerulopathy Developed at the Time of Transition from Chronic Myelogenous Leukemia to Myelodysplastic Syndrome: A Case Report"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<p>Myelodysplastic syndrome (MDS) often coexists with systemic autoimmune diseases. Chronic myelogenous leukemia (CML) is an independent risk factor for intrarenal arterial hyalinosis. We describe a case of glomerulopathy that developed at the transition from CML with 5q deletion (relatively rare) to MDS with 5q and 13q deletion. Kidney histology showed glomerular hyalinosis due to intrarenal arterial changes from CML, in addition to podocytic infolding glomerulopathy (PIG) due to systemic immune responses from MDS or tyrosine kinase inhibitors, or which was coincidental. To our knowledge, this is the first case of PIG developing during the transition from CML to MDS. </p>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410588369390010753","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Nakamori Aya"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Nephrology, Otemae Hospital, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410588369390010754","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Saito Norimitsu"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Hematology, Otemae Hospital, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410588369390010752","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Akagak Fuyuko"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Nephrology, Otemae Hospital, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09182918"},{"@type":"EISSN","@value":"13497235"}],"prism:publicationName":[{"@language":"en","@value":"Internal Medicine"},{"@language":"en","@value":"Intern. Med."}],"dc:publisher":[{"@language":"en","@value":"The Japanese Society of Internal Medicine"},{"@language":"ja","@value":"一般社団法人 日本内科学会"}],"prism:publicationDate":"2026","prism:volume":"advpub","prism:number":"0"},"reviewed":"false","datacite:version":"1","url":[{"@id":"https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_6455-25/_pdf"}],"availableAt":"2026","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=urine%20protein","dc:title":"urine protein"},{"@id":"https://cir.nii.ac.jp/all?q=podocytic%20infolding%20glomerulopathy","dc:title":"podocytic infolding glomerulopathy"},{"@id":"https://cir.nii.ac.jp/all?q=chronic%20myelogenous%20leukemia","dc:title":"chronic myelogenous leukemia"},{"@id":"https://cir.nii.ac.jp/all?q=myelodysplastic%20syndrome","dc:title":"myelodysplastic syndrome"},{"@id":"https://cir.nii.ac.jp/all?q=5q%20deletion","dc:title":"5q deletion"},{"@id":"https://cir.nii.ac.jp/all?q=13q%20deletion","dc:title":"13q deletion"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360305498296530688","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Podocyte Infolding Glomerulopathy: A Case Series Report and Literature Review"}]},{"@id":"https://cir.nii.ac.jp/crid/1360307277188532864","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Tyrosine Kinase Inhibitor Induced Proteinuria – A\n                    Review"}]},{"@id":"https://cir.nii.ac.jp/crid/1360307280268676352","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Philadelphia chromosome positive chronic myeloid leukemia with 5q deletion at diagnosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360307280709581312","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Kidney involvement in myelodysplastic syndromes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567189341751936","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Favorable outcome of patients who have 13q deletion: a suggestion for revision of the WHO 'MDS-U' designation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360588753926660224","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Subepithelial deposits with microspherular structures in membranous glomerulonephritis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360870230668716800","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The spectrum of glomerular and vascular kidney pathology associated with myeloproliferative neoplasms"}]},{"@id":"https://cir.nii.ac.jp/crid/1360870231975339776","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Spectrum of Kidney Involvement in Patients with Myelodysplastic Syndromes"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107371329915776","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Proteinuria and hypertension with tyrosine kinase inhibitors"}]},{"@id":"https://cir.nii.ac.jp/crid/2050025942148734592","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A case of long-term dasatinib-induced proteinuria and glomerular injury"}]},{"@id":"https://cir.nii.ac.jp/crid/2051714792003037312","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Proposal of podocytic infolding glomerulopathy as a new disease entity : a review of 25 cases from nationwide research in Japan"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:9200083297"},{"@type":"CROSSREF","@value":"10.2169/internalmedicine.6455-25"},{"@type":"PUBMED","@value":"41535031"}]}