職域集団の脂質異常症判定における肥満指標（BMIと腹囲）の妥当性の検討

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  • Validity of BMI and waist circumference in the diagnosis of dyslipidemia in a worksite population
  • ショクイキ シュウダン ノ シシツ イジョウショウ ハンテイ ニ オケル ヒマン シヒョウ(BMI ト フクイ)ノ ダトウセイ ノ ケントウ

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<p>　The purpose of this study is to examine the validity of two obesity indices, BMI and waist circumference （WC）, regarding the diagnosis of dyslipidemia among a worksite population. Worksite annual health check-up data in 2013 involving 15,289 subjects were utilized for this study. After subjects with missing values, on lipid-lowering medication, with TG values of ≥ 600 mg/dl, under 20 years or over 60 years of age, and smokers were excluded, we eventually analyzed 8,189 subjects （3,990 men, 4,199 women）. In this population, the diagnostic validity of the following three cut-off values was evaluated: 1） BMI ≥ 25 （BMI criteria）, 2） WC ≥ 85 cm （men） and ≥ 90 cm （women） （JASSO WC criteria）, and 3） WC ≥ 90 cm （men） and ≥ 80 cm （women） （WHO WC criteria）. Among each age and sex strata, relatively high odds ratios were observed for high triglyceridemia （TG ≥ 150 mg/dl） and low HDL-cholesterolemia （HDL-C＜40 mg/dl）, especially when both the JASSO and WHO WC criteria were used. The ROC curve analysis showed moderately high diagnostic abilities of both BMI and WC for high TG and low HDL-cholesterol values with the AUC range of 0.70 to 0.79 and that the appropriate BMI and WC cut-off values were 23 and 80 cm for both the men and women, respectively.</p><p>　In this population, both BMI and WC were related to high triglyceridemia and low HDL-cholesterolemia, and the appropriate cut-off values for both of these conditions were BMI of 23 and WC of 80 cm for both the men and women.</p>

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