A report on the risk of the second primary malignancy of the oral cancer

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  • Mizumoto Yui
    Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, the University of Tokyo Hospital
  • Saito Yuki
    Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, the University of Tokyo Hospital
  • Sakai Toshihiko
    Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, the University of Tokyo Hospital
  • Fukuoka Osamu
    Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, the University of Tokyo Hospital
  • Ando Mizuo
    Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, the University of Tokyo Hospital
  • Yamasoba Tatsuya
    Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, the University of Tokyo Hospital

Bibliographic Information

Other Title
  • 口腔癌における重複癌のリスク因子に関する検討
Published
2021
DOI
  • 10.5106/jjshns.31.141
Publisher
JAPAN SOCIETY FOR HEAD AND NECK SURGERY

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Background. Head and neck cancers account for a relatively large number of second primary malignancies （SPM）. It is important to search for SPM in the head and neck area and the upper gastrointestinal tract. In addition, there are few reports in Japan on the risk of SPM of oral cancer.<br>Methods. A retrospective study was conducted on 155 oral cancer patients treated at our hospital.<br>Results. There were 47 cases that developed SPM, in which 11 developed synchronously and 39 developed metachronously: three cases developed SPM both synchronously and metachronously. The risk factors for SPM were smoking history of 25 packs/year or more for synchronous SPM and 37 packs/year or more and age （67 years or older） for metachronous SPM, and fewer than three cases of young or non-smoking metachronous SPM of the upper gastrointestinal tract.<br>Conclusion. Duplicate cancer search is less likely to focus on the upper gastrointestinal tract in younger or non-smoking patients.

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