In vitro Azole Susceptibility Testing of Japanese Isolates of Terbinafine-Resistant Trichophyton indotineae and Trichophyton rubrum
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- Hiruma Junichiro
- Department of Dermatology, Tokyo Medical University Teikyo University Institute of Medical Mycology (TIMM)
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- Kimura Utako
- Department of Dermatology, Juntendo University Urayasu Hospital
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- Noguchi Hiromitsu
- Noguchi Dermatology Clinic
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- Hiruma Masataro
- Ochanomizu Institute for Medical Mycology and Allergology
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- Harada Kazutoshi
- Department of Dermatology, Tokyo Medical University
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- Kano Rui
- Teikyo University Institute of Medical Mycology (TIMM)
書誌事項
- タイトル別名
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- <i>In vitro</i> Azole Susceptibility Testing of Japanese Isolates of Terbinafine-Resistant <i>Trichophyton indotineae</i> and <i>Trichophyton rubrum</i>
この論文をさがす
説明
Multi-antifungal-resistant strains of Trichophyton indotineae and Trichophyton rubrum have been isolated in Japan. In the present study, we examined the in vitro susceptibility of terbinafine (TRBF) -resistant isolates of T. indotineae and T. rubrum to efinaconazole (EFCZ) and luliconazole (LUCZ). In all isolates, the minimum inhibitory concentrations were ≥ 32 mg/l for TRBF, < 0.03 to 16 mg/l for itraconazole, < 0.03 to 16 mg/l for ravuconazole, < 0.03 to 0.5 mg/l for LUCZ, and < 0.03 to 4 mg/l for EFCZ. Of note, T. rubrum NUBS21012 and T. indotineae NUBS 19006T showed resistance to LUCZ and/or EFCZ unlike the other isolates.
収録刊行物
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- Medical Mycology Journal
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Medical Mycology Journal 64 (1), 23-25, 2023
日本医真菌学会
