{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390858441645615744.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.14951/jsnc.25-001"}},{"identifier":{"@type":"HDL","@value":"https://hdl.handle.net/2324/6781058"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2023163998"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Right Ventricular Strain Derived from <sup>13</sup>N-ammonia PET and Myocardial Ischemia"},{"@language":"ja","@value":"高解像<sup>13</sup>N-アンモニアPET画像の feature-trackingによる右心室ストレインと心筋虚血との関連"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<b><i>Objective</i></b>: It is important to assess myocardial motion for not only left ventricle but also right ventricle. We developed a feature-tracking (FT) algorithm for use with electrocardiography-gated high-resolution <sup>13</sup>N-ammonia positron emission tomography (PET) imaging. Previously, we reported that the left ventricular strain value derived from PET-FT analysis can detect a decrease of ischemic myocardium motion. Further, the PET-derived left ventricular longitudinal strain (LS) value was validated referred to cardiac magnetic resonance. In the present research, we applied right ventricular (RV) strain analysis based on the FT algorithm to high-resolution <sup>13</sup>N-ammonia PET images, and investigated the association between myocardial ischemia and RV myocardial motion.<br><b><i>Methods</i></b>: Ninety-three patients with coronary artery stenosis >50%, diagnosed by coronary computed tomography angiography, and 10 controls were retrospectively analyzed. RV-LS in the free wall was measured by a FT technique on the resting and stressed <sup>13</sup>N-ammonia PET images of horizontal long-axis slices. The patients were sub-grouped according to summed stress score (SSS) values: SSS>12 as severe ischemia [n=13], 4≤SSS≤12 as moderate ischemia [n=29], and SSS<4 as normal [n=51]. Stress and resting RV-LS were compared in each of the four groups. Multiple comparisons of RV-LS among the four groups were performed in the stress and resting state.<br><b><i>Results</i></b>: Decreased absolute RV-LS values at stress in the groups of severe and moderate ischemia were observed with respect to those in the groups of normal and control. Increased absolute RV-LS values at stress state in patients with normal and control were observed with respect to those at resting state.<br><b><i>Conclusion</i></b>: We measured RV myocardial LS using FT in high-resolution cine imaging of <sup>13</sup>N-ammonia PET. The results of this study suggest that PET-derived RV-LS is useful for detecting reduced RV myocardial motion due to ischemia in the patients with coronary artery disease."},{"@language":"ja","@value":"<b>目的</b>：<sup>13</sup>N-アンモニア PETから右室長軸ストレイン（RV-LS）解析を開発し、心筋虚血と右室壁運動との関連を検討した。<br><b>方法</b>：冠動脈病変もしくは冠動脈病変疑いで<sup>13</sup>N-アンモニア PET検査が施行された 93名を summed stress score（SSS）によって、SSS>12の重症虚血群、4≤SSS≤12の中等度群、SSS<4の正常群に分けた。さらに、冠動脈狭窄と過去の梗塞歴のない患者を無作為に 10名抽出して対照群とした。各群の負荷時と安静時の RV-LSを比較した。<br><b>結果</b>：重症虚血群および中等度虚血群の負荷時の RV-LSの絶対値は、正常群および対照群よりも低かった。正常群および対照群において負荷時の RV-LSの絶対値は、安静時に対して増加した。<br><b>結論</b>：<sup>13</sup>N-アンモニア PETストレイン解析は心筋虚血に伴う右室壁運動低下を定量する新技術である。"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420282801201945344","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"80608985"},{"@type":"NRID","@value":"1000080608985"},{"@type":"ORCID","@value":"0000-0003-1867-1745"},{"@type":"NRID","@value":"9000415307152"},{"@type":"NRID","@value":"9000412584123"},{"@type":"NRID","@value":"9000412584148"},{"@type":"NRID","@value":"9000006556612"},{"@type":"NRID","@value":"9000412584134"},{"@type":"NRID","@value":"9000412228957"},{"@type":"NRID","@value":"9000410922199"},{"@type":"NRID","@value":"9000410978161"},{"@type":"NRID","@value":"9000414483213"},{"@type":"NRID","@value":"9000403546215"},{"@type":"NRID","@value":"9000415343634"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/masateru_kawakubo"}],"foaf:name":[{"@language":"en","@value":"Kawakubo Masateru"},{"@language":"ja","@value":"河窪 正照"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Health Sciences, Faculty of Medical Sciences, Kyushu University"},{"@language":"ja","@value":"九州大学大学院医学研究院保健学部門"}]},{"@id":"https://cir.nii.ac.jp/crid/1420564276187468800","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"60533081"},{"@type":"NRID","@value":"1000060533081"},{"@type":"ORCID","@value":"0000-0001-6049-8857"},{"@type":"NRID","@value":"9000265248789"},{"@type":"NRID","@value":"9000413573613"},{"@type":"NRID","@value":"9000412584150"},{"@type":"NRID","@value":"9000415187132"},{"@type":"NRID","@value":"9000256911706"},{"@type":"NRID","@value":"9000410978162"},{"@type":"NRID","@value":"9000413779932"},{"@type":"NRID","@value":"9000403546211"},{"@type":"NRID","@value":"9000397423776"},{"@type":"NRID","@value":"9000414518188"}],"foaf:name":[{"@language":"en","@value":"Nagao Michinobu"},{"@language":"ja","@value":"長尾 充展"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University"},{"@language":"ja","@value":"東京女子医科大学画像診断学・核医学講座"}]},{"@id":"https://cir.nii.ac.jp/crid/1410858441645615749","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Yamamoto Atsushi"},{"@language":"ja","@value":"山本 篤志"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"東京女子医科大学画像診断学・核医学講座"},{"@language":"en","@value":"Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410858441645615753","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Nakao Risako"},{"@language":"ja","@value":"中尾 梨沙子"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Cardiology, Tokyo Women's Medical University"},{"@language":"ja","@value":"東京女子医科大学循環器内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410858441645615747","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Matsuo Yuka"},{"@language":"ja","@value":"松尾 有香"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"東京女子医科大学画像診断学・核医学講座"},{"@language":"en","@value":"Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410858441645615746","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Kaneko Koichiro"},{"@language":"ja","@value":"金子 恒一郎"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University"},{"@language":"ja","@value":"東京女子医科大学画像診断学・核医学講座"}]},{"@id":"https://cir.nii.ac.jp/crid/1410858441645615750","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Watanabe Eri"},{"@language":"ja","@value":"渡邊 絵里"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"東京女子医科大学循環器内科"},{"@language":"en","@value":"Department of Cardiology, Tokyo Women's Medical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410858441645615748","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Sakai Akiko"},{"@language":"ja","@value":"坂井 晶子"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Cardiology, Tokyo Women's Medical University"},{"@language":"ja","@value":"東京女子医科大学循環器内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410858441645615752","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Sasaki Masayuki"},{"@language":"ja","@value":"佐々木 雅之"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Health Sciences, Faculty of Medical Sciences, Kyushu University"},{"@language":"ja","@value":"九州大学大学院医学研究院保健学部門"}]},{"@id":"https://cir.nii.ac.jp/crid/1410858441645615751","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Sakai Shuji"},{"@language":"ja","@value":"坂井 修二"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University"},{"@language":"ja","@value":"東京女子医科大学画像診断学・核医学講座"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13462733"},{"@type":"EISSN","@value":"24241733"},{"@type":"NCID","@value":"AA12746913"}],"prism:publicationName":[{"@language":"ja","@value":"心臓核医学"},{"@language":"en","@value":"SHINZO KAKU IGAKU"}],"dc:publisher":[{"@language":"en","@value":"Japanese Society of Nuclear Cardiology"},{"@language":"ja","@value":"日本心臓核医学会"}],"prism:publicationDate":"2023","prism:volume":"25","prism:number":"1","prism:startingPage":"13","prism:endingPage":"17"},"dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"https://search.jamas.or.jp/link/ui/2023163998"}],"availableAt":"2023","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%3Csup%3E13%3C/sup%3EN-ammonia%20PET","dc:title":"<sup>13</sup>N-ammonia PET"},{"@id":"https://cir.nii.ac.jp/all?q=Feature-tracking","dc:title":"Feature-tracking"},{"@id":"https://cir.nii.ac.jp/all?q=High-resolution%20cine%20imaging","dc:title":"High-resolution cine imaging"},{"@id":"https://cir.nii.ac.jp/all?q=Myocardial%20ischemia","dc:title":"Myocardial ischemia"},{"@id":"https://cir.nii.ac.jp/all?q=Right%20ventricular%20strain","dc:title":"Right ventricular strain"}],"dcterms:subject":[{"subjectScheme":"Other","notation":[{"@language":"en","@value":"^<13>N-ammonia PET"}]},{"subjectScheme":"Other","notation":[{"@language":"en","@value":"Feature-tracking"}]},{"subjectScheme":"Other","notation":[{"@language":"en","@value":"High-resolution cine imaging"}]},{"subjectScheme":"Other","notation":[{"@language":"en","@value":"Myocardial ischemia"}]},{"subjectScheme":"Other","notation":[{"@language":"en","@value":"Right ventricular strain"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:2010327898"},{"@type":"IRDB","@value":"oai:irdb.nii.ac.jp:01211:0005990005"}]}