Comparison of Discriminative Ability of Bleeding Risk Criteria and Scores for Predicting Short- and Mid-Term Major Bleeding Events in Patients Undergoing Percutaneous Coronary Intervention

  • Shimono Hirokazu
    Department of Cardiovascular Medicine, Kagoshima City Hospital Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University
  • Tokushige Akihiro
    Department of Prevention and Analysis of Cardiovascular Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University Department of Clinical Pharmacology and Therapeutics, University of the Ryukyus School of Medicine
  • Kanda Daisuke
    Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University
  • Ohno Ayaka
    Department of Cardiovascular Medicine, Kagoshima City Hospital
  • Arikawa Ryo
    Department of Cardiovascular Medicine, Kagoshima City Hospital
  • Chaen Hideto
    Department of Cardiovascular Medicine, Kagoshima City Hospital
  • Okui Hideki
    Department of Cardiovascular Medicine, Kagoshima City Hospital
  • Oketani Naoya
    Department of Cardiovascular Medicine, Kagoshima City Hospital
  • Ohishi Mitsuru
    Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University Department of Prevention and Analysis of Cardiovascular Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University

Bibliographic Information

Published
2024-01-10
DOI
  • 10.1253/circrep.cr-23-0087
Publisher
The Japanese Circulation Society

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Description

<p>Background: This study aimed to compare the discriminative ability of the Japanese Version of High Bleeding Risk (J-HBR), Academic Research Consortium for High Bleeding Risk (ARC-HBR), and Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy (PRECISE-DAPT) scores for predicting major bleeding events.</p><p>Methods and Results: Between January 2017 and December 2020, 646 consecutive patients who underwent successful percutaneous coronary intervention (PCI) were enrolled. We scored the ARC-HBR and J-HBR criteria by assigning 1 point to each major criterion and 0.5 point to each minor criterion. The primary outcome was major bleeding events, defined as Bleeding Academic Research Consortium type 3 or 5 bleeding events. According to the J-HBR, ARC-HBR, and PRECISE-DAPT scores, 428 (66.3%), 319 (49.4%), and 282 (43.7%) patients respectively had a high bleeding risk. During the follow-up period (median, 974 days), 44 patients experienced major bleeding events. The area under the curve (AUC) using the time-dependent receiver operating characteristic curve for major bleeding events was 0.84, 0.82, and 0.83 within 30 days and 0.86, 0.83, and 0.80 within 2 years for the J-HBR, ARC-HBR, and PRECISE-DAPT scores, respectively. The AUC values did not differ significantly among the 3 bleeding risk scores.</p><p>Conclusions: The J-HBR score had a discriminative ability similar to the ARC-HBR and PRECISE-DAPT scores for predicting short- and mid-term major bleeding events.</p>

Journal

  • Circulation Reports

    Circulation Reports 6 (1), 4-15, 2024-01-10

    The Japanese Circulation Society

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