{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390865950718197504.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3805/eands.a000162"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/eands/17/0/17_A000162/_pdf"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2026008022"}}],"dc:title":[{"@language":"en","@value":"Ictal 1.5-Tesla MR imaging with arterial spin labeling perfusion imaging in          three patients with electrographic seizures diagnosed with routine electroencephalography          based on the ACNS Critical Care EEG Terminology 2021"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<p><i>Background</i>: The 2021 version of the Standardized Critical Care EEG          Terminology published by the American Clinical Neurophysiology Society (ACNS 2021)          specifies the diagnostic criteria for non-convulsive status epilepticus (NCSE) using          continuous electroencephalographic (cEEG) monitoring. Since few facilities have access to          cEEG, routine EEG, which can only be performed during consultation hours, is generally          used for emergencies. We examined if the diagnostic ability is enhanced by adding arterial          spin labeling (ASL) perfusion imaging to 1.5-Tesla magnetic resonance imaging (MRI).            <i>Patients and Methods</i>: Eighty EEGs, performed on patients with          neurological emergencies for 2 years, were reviewed which included three patients          diagnosed with electrographic seizures (ESz). <i>Results</i>: Based on the          ACNS21, EEG could diagnose Esz, but could not diagnose NCSE, being a 30-minute recording.          In contrast, ASL clearly identified focal, ictal hyperperfusion. The signal intensity was          maximized at a post-labeling delay (PLD) of 1.5-1.75 s. The signal intensity gradually          decreased. However, even at a PLD of 2.0 s, the intensity remained strong in areas with a          close anatomical relationship to the epileptogenic lesions. Further, the same region          showed high signal intensity on diffusion-weighted imaging (DWI).            <i>Conclusion:</i> Although ESz can be diagnosed based on the ACNS 2021 using          EEG alone, diagnosing NCSE can be challenging. Therefore, our suggestion is to initially          perform MRI to capture the hemodynamics of ictal hyperperfusion using ASL with multiple          PLDs, and monitor the coupling state of metabolism and blood flow with DWI. Finally, an          accurate pathophysiological diagnosis of NCSE should be confirmed by EEG. </p>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410865950718197377","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Morioka Takato"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Hachisuga Hospital, Munakata, Fukuoka,              Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197508","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Mugita Fumihito"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Hachisuga Hospital, Munakata, Fukuoka,              Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197509","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Inoha Satoshi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Hachisuga Hospital, Munakata, Fukuoka,              Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197379","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Akiyama Tomoaki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu              University, Fukuoka, Fukuoka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197378","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Haruyama Hironori"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu              University, Fukuoka, Fukuoka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197376","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Karashima Satoshi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu              University, Fukuoka, Fukuoka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197504","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Shimogawa Takafumi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu              University, Fukuoka, Fukuoka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197505","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Mukae Nobutaka"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu              University, Fukuoka, Fukuoka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197506","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Sakata Ayumi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Clinical Laboratory, Kyushu University Hospital, Fukuoka,              Fukuoka, Japan"},{"@language":"en","@value":"Division of Medical Technology, Department of Health Sciences, Graduate              School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197507","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Shigeto Hiroshi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Division of Medical Technology, Department of Health Sciences, Graduate              School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, Japan"},{"@language":"en","@value":"Department of Neurology, Graduate School of Medical Sciences, Kyushu              University, Fukuoka, Fukuoka, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410865950718197510","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Yoshimoto Koji"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu              University, Fukuoka, Fukuoka, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"18825567"}],"prism:publicationName":[{"@language":"en","@value":"Epilepsy & Seizure"},{"@language":"en","@value":"E&S"}],"dc:publisher":[{"@language":"en","@value":"JAPAN EPILEPSY SOCIETY"},{"@language":"ja","@value":"一般社団法人 日本てんかん学会"}],"prism:publicationDate":"2025","prism:volume":"17","prism:number":"0","prism:startingPage":"n/a"},"reviewed":"false","url":[{"@id":"https://www.jstage.jst.go.jp/article/eands/17/0/17_A000162/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2026008022"}],"availableAt":"2025","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Arterial%20spin%20labeling","dc:title":"Arterial spin labeling"},{"@id":"https://cir.nii.ac.jp/all?q=Critical%20care%20EEG","dc:title":"Critical care EEG"},{"@id":"https://cir.nii.ac.jp/all?q=Diffusion-weighted%20imaging","dc:title":"Diffusion-weighted imaging"},{"@id":"https://cir.nii.ac.jp/all?q=Ictal%20hyperperfusion","dc:title":"Ictal hyperperfusion"},{"@id":"https://cir.nii.ac.jp/all?q=Non-convulsive%20status%20epilepticus","dc:title":"Non-convulsive status epilepticus"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360016870116221824","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Simultaneous Electroencephalographic and Electocorticographic Recordings of Lateralized Periodic Discharges in Temporal Lobe Epilepsy"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292617911523968","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A definition and classification of status epilepticus – Report of the\n                    <scp>ILAE</scp>\n                    Task Force on Classification of Status Epilepticus"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620110465408","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Epileptic Ictal Hyperperfusion on Arterial Spin Labeling Perfusion and Diffusion-Weighted Magnetic 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labeling perfusion MR images and time-of-flight MR angiography in the detection of periictal hyperperfusion"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994361094016","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Usefulness of arterial spin-labeling images in periictal state diagnosis of epilepsy"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544420452629888","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Nonconvulsive Partial Status Epilepticus Mimicking Recurrent Infarction Revealed by Diffusion-weighted and Arterial Spin Labeling Perfusion Magnetic Resonance Images"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544420784298240","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Unified <scp>EEG</scp> terminology and criteria for nonconvulsive status 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imaging"}]},{"@id":"https://cir.nii.ac.jp/crid/1390858851008501504","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Hemodynamics of ictal hyperperfusion in an epileptic patient with dual pathology revealed by arterial spin labeling perfusion image with triple postlabeling delays"}]},{"@id":"https://cir.nii.ac.jp/crid/1390860532059129856","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Detection of slightly increased signals in temporal lobe on periictal arterial spin labeling perfusion image for initial suspicion of temporal lobe epilepsy"}]},{"@id":"https://cir.nii.ac.jp/crid/1390862853908419584","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Addition of 1.5-Tesla arterial spin labeling magnetic resonance perfusion imaging to routine electroencephalography in pathophysiological diagnosis of first-onset generalized convulsive seizures 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