Clinicopathological Analysis of Ovarian Tumor in Postmenopausal Women

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  • IWANAGA,Kumi
    Department of Obstetrics and Gynecology, Kitasato University, School of Medicine
  • JOBO,Toshiko
    Department of Obstetrics and Gynecology, Kitasato University, School of Medicine
  • SATOH,Rinya
    Department of Obstetrics and Gynecology, Kitasato University, School of Medicine
  • KURAMOTO,Hiroyuki
    Department of Obstetrics and Gynecology, Kitasato University, School of Medicine
  • NISHIJIMA,Masahiro
    Department of Obstetrics and Gynecology, Kitasato University, School of Medicine

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  • 閉経後における卵巣腫瘍の臨床病理学的検討

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The objective of this paper is to discuss and evaluate the diagnosis and management of ovarian masses in postmenopausal women. A group of 230 postmenopausal patients with ovarian tumors, aged 50 years or over were the subjects of the study. 1. Ninety-nine (43.1%) had malignant tumors (serous adenocarcinoma : 58, clear cell adenocarcinoma : 16, mucinous adenocarcinoma : 14, endometrioid adenocarcinoma : 6 and malignant transformation of dermoid cyst : 2), 12 (5.2%) had borderline malignant tumors (mucinous cystadenoma : 8 and granulosa cell tumor : 4) and 119 (51.7%) had benign tumors (mucinous cystadenoma : 40, serous cystadenoma : 35, dermoid cyst : 29, endometrioid cyst : 6, and fibroma : 6). 2. Their ages ranged from 50 to 98 years (mean : 61.9) 55 patients were in the 55-59 year age group and 52 in the 50-54 year age group. The malignancy rates were 52-56% in the 55-69 year age groups, but decreased in the patients over 70 years of age. 3. Chief complaints were abdominal distension (59 cases), abdominal pain (49 cases), an abdominal mass (38 cases) and genital bleeding (30 cases). Forty-four patients without any complaint were found by manual examination in a routine gynecological check-up, and had a significantly lower malignancy rate. 4. The size of the tumor was measured by ultrasonography in 176 patients. The diameter of tumor was 7cm or less in 18 cases, 7-10cm in 32 cases and 10cm or more in 125 cases. The incidences of malignant tumor were 66.7%, 37.5% and 45.6%, respectively. 5. Since the incidence of malignant tumors after menopause is high, even small masses less than 7cm in diameter should be detect for malignancy by image analysis and tumor markers.

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