{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1570009752551889792.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"NAID","@value":"110003654777"}}],"dc:title":[{"@language":"en","@value":"Reaction of Cyclic Silyl Phosphites with Haloacetones"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"The reaction of cyclic silyl phosphites (2) with haloacetones (3) was in vestigated. When oxirane compounds were used as scavengers of trimethylsily halides, cyclic acetonylphosphonates (4) were obtained directly. Treatment of 2-trimethylsilyloxy-1,3,2-dioxaphosphorinane (2a) with bromoacetone (3b) or iodoacetone (3c) in propylene oxide gave 4a in 24% and 41% yields, respectively. With cyclohexane oxide, the reaction of 2a with 3c in MeCN at reflux gave 4a in 50% yield. Treatment of 5,5-dimethyl-2-trimethylsilyloxy-1,3,2-dioxaphosphorinane (2b) with 3c in the same manner gave 4b in 43% yield."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1580009752551889793","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"森田 岩男"},{"@language":"en","@value":"MORITA IWAO"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Research Laboratories, Nippon Shinyaku Co., Ltd.,"}]},{"@id":"https://cir.nii.ac.jp/crid/1580009752551889792","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000005276872"}],"foaf:name":[{"@language":"ja","@value":"畳開 庄一"},{"@language":"en","@value":"CHOKAI SHOICHI"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Research Laboratories, Nippon Shinyaku Co., Ltd.,"}]},{"@id":"https://cir.nii.ac.jp/crid/1580009752551889664","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000005276873"}],"foaf:name":[{"@language":"ja","@value":"津田 正己"},{"@language":"en","@value":"TSUDA MASAMI"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Research Laboratories, Nippon Shinyaku Co., Ltd.,"}]},{"@id":"https://cir.nii.ac.jp/crid/1580009752551889794","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"黄瀬 正博"},{"@language":"en","@value":"KISE MASAHIRO"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Research Laboratories, Nippon Shinyaku Co., Ltd.,"}]},{"@id":"https://cir.nii.ac.jp/crid/1580009752551889795","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"杉山 信"},{"@language":"en","@value":"SUGIYAMA MAKOTO"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Research Laboratories, Nippon Shinyaku Co., Ltd.,"}]}],"publication":{"publicationIdentifier":[{"@type":"ISSN","@value":"00092363"},{"@type":"NCID","@value":"AA00602100"}],"prism:publicationName":[{"@language":"en","@value":"Chemical & pharmaceutical bulletin"}],"dc:publisher":[{"@value":"公益社団法人日本薬学会"},{"@language":"en","@value":"The Pharmaceutical Society of Japan"}],"prism:publicationDate":"1988-03-25","prism:volume":"36","prism:number":"3","prism:startingPage":"1135","prism:endingPage":"1138"},"foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=cyclic%20silyl%20phosphite","dc:title":"cyclic silyl phosphite"},{"@id":"https://cir.nii.ac.jp/all?q=haloacetone","dc:title":"haloacetone"},{"@id":"https://cir.nii.ac.jp/all?q=cyclic%20acetonylphosphonate","dc:title":"cyclic acetonylphosphonate"},{"@id":"https://cir.nii.ac.jp/all?q=enolphosphate","dc:title":"enolphosphate"},{"@id":"https://cir.nii.ac.jp/all?q=Arbuzov%20reaction","dc:title":"Arbuzov reaction"},{"@id":"https://cir.nii.ac.jp/all?q=Perkow%20reaction","dc:title":"Perkow reaction"},{"@id":"https://cir.nii.ac.jp/all?q=carbonyl%20adduct","dc:title":"carbonyl adduct"},{"@id":"https://cir.nii.ac.jp/all?q=trimethylsilyl%20halide%20scavenger","dc:title":"trimethylsilyl halide scavenger"},{"@id":"https://cir.nii.ac.jp/all?q=cyclic%20silyl%20phosphite","dc:title":"cyclic silyl phosphite"},{"@id":"https://cir.nii.ac.jp/all?q=haloacetone","dc:title":"haloacetone"},{"@id":"https://cir.nii.ac.jp/all?q=cyclic%20acetonylphosphonate","dc:title":"cyclic acetonylphosphonate"},{"@id":"https://cir.nii.ac.jp/all?q=enolphosphate","dc:title":"enolphosphate"},{"@id":"https://cir.nii.ac.jp/all?q=Arbuzov%20reaction","dc:title":"Arbuzov reaction"},{"@id":"https://cir.nii.ac.jp/all?q=Perkow%20reaction","dc:title":"Perkow reaction"},{"@id":"https://cir.nii.ac.jp/all?q=carbonyl%20adduct","dc:title":"carbonyl adduct"},{"@id":"https://cir.nii.ac.jp/all?q=trimethylsilyl%20halide%20scavenger","dc:title":"trimethylsilyl halide scavenger"}],"dataSourceIdentifier":[{"@type":"CIA","@value":"110003654777"}]}