Visualization of Interval Changes of Pulmonary Nodules Using High-Resolution CT Images

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This paper presents a method to analyze volumetrically evolutions of pulmonary nodules for discrimination between malignant and benign nodules. Our method consists of four steps; (1)The 3-D rigid registration of the two successive 3-D thoracic CT images, (2)the 3-D affine registration of the two successive region-of-interest(ROI)images, (3)non-rigid registration between local volumetric ROIs, and(4)analysis of the local displacement field between successive temporal images. In the preliminary study, the method was applied to the successive 3-D thoracic images of two pulmonary nodules including a metastasis malignant nodule and a inflammatory benign nodule to quantify evolutions of the pulmonary nodules and their surrounding structures. The time intervals between successive 3-D thoracic images for the benign and malignant cases were 150 and 30 days, respectively. From the display of the displacement fields and the contrasted image by the vector field operator based on the Jacobian, it was observed that the benign case reduced in the volume and the surrounding structure was involved into the nodule. It was also observed that the malignant case expanded in the volume. These experimental results indicate that our method is a promising tool to quantify how the lesions evolve their volume and surrounding structures.

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詳細情報 詳細情報について

  • CRID
    1574231877209062144
  • NII論文ID
    110003210600
  • NII書誌ID
    AA10826272
  • ISSN
    09168532
  • 本文言語コード
    en
  • データソース種別
    • CiNii Articles

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