{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1872272492418616320.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/s0040-4020(02)00654-3"}},{"identifier":{"@type":"DOI","@value":"10.1002/chin.200250208"}}],"dc:title":[{"@value":"Hedathiosulfonic acids A and B, novel thiosulfonic acids from the deep-sea urchin Echinocardium cordatum"}],"description":[{"notation":[{"@value":"Abstract   Hedathiosulfonic acids A and B were isolated from the deep-sea urchin Echinocardium cordatum and were determined to be novel 6-undecanethiosulfonic acids by 2D NMR, HRMS, and methylation reaction. The stereostructure of hedathiosulfonic acid A was determined by the analysis of its degradation product, a cyclic β-hydroxysulfone. Hedathiosulfonic acids exhibited acute toxicity. We carried out various model reactions of the olefinic compounds with thiosulfonic acids and proved that, as is the case with natural products, synthesized thiosulfonic acid possessing a carbon–carbon double bond was converted into β-hydroxysulfone in the presence of oxygen."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1892272492418616324","@type":"Researcher","foaf:name":[{"@value":"Kaoru Yamada"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492418616321","@type":"Researcher","foaf:name":[{"@value":"Daisuke Uemura"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492418616320","@type":"Researcher","foaf:name":[{"@value":"Masaki Kita"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492418616323","@type":"Researcher","foaf:name":[{"@value":"Masami Watanabe"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492418616325","@type":"Researcher","foaf:name":[{"@value":"Noboru Takada"}]},{"@id":"https://cir.nii.ac.jp/crid/1420845751152646144","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"60273215"},{"@type":"NRID","@value":"1000060273215"},{"@type":"NRID","@value":"9000257886687"},{"@type":"NRID","@value":"9000257726817"},{"@type":"NRID","@value":"9000006765577"},{"@type":"NRID","@value":"9000256030416"},{"@type":"NRID","@value":"9000258471513"},{"@type":"NRID","@value":"9000009546413"},{"@type":"NRID","@value":"9000404088549"},{"@type":"NRID","@value":"9000396141310"},{"@type":"NRID","@value":"9000015511534"},{"@type":"NRID","@value":"9000283737387"},{"@type":"NRID","@value":"9000347084351"},{"@type":"NRID","@value":"9000347084702"},{"@type":"NRID","@value":"9000396141498"},{"@type":"NRID","@value":"9000257720828"},{"@type":"NRID","@value":"9000020786071"},{"@type":"NRID","@value":"9000383838359"},{"@type":"NRID","@value":"9000256024658"},{"@type":"NRID","@value":"9000257717012"},{"@type":"NRID","@value":"9000001210752"},{"@type":"NRID","@value":"9000317133171"},{"@type":"NRID","@value":"9000383838749"},{"@type":"NRID","@value":"9000000873073"},{"@type":"NRID","@value":"9000024267538"},{"@type":"NRID","@value":"9000256023556"},{"@type":"NRID","@value":"9000256029189"},{"@type":"NRID","@value":"9000019145386"},{"@type":"NRID","@value":"9000391396708"},{"@type":"NRID","@value":"9000242707825"},{"@type":"NRID","@value":"9000001284088"},{"@type":"NRID","@value":"9000367031777"},{"@type":"NRID","@value":"9000283393751"},{"@type":"NRID","@value":"9000243752107"},{"@type":"NRID","@value":"9000398281927"},{"@type":"NRID","@value":"9000254577757"},{"@type":"NRID","@value":"9000258471140"},{"@type":"NRID","@value":"9000257722241"},{"@type":"NRID","@value":"9000002106669"},{"@type":"NRID","@value":"9000019059276"},{"@type":"NRID","@value":"9000238246282"},{"@type":"NRID","@value":"9000024152661"},{"@type":"NRID","@value":"9000305637175"},{"@type":"NRID","@value":"9000353367208"},{"@type":"NRID","@value":"9000257735125"},{"@type":"NRID","@value":"9000016591358"},{"@type":"NRID","@value":"9000243751882"},{"@type":"NRID","@value":"9000404530907"},{"@type":"NRID","@value":"9000391922727"},{"@type":"NRID","@value":"9000258471516"},{"@type":"NRID","@value":"9000257721321"},{"@type":"NRID","@value":"9000257717233"},{"@type":"NRID","@value":"9000397855546"},{"@type":"NRID","@value":"9000001126838"},{"@type":"NRID","@value":"9000020193490"},{"@type":"NRID","@value":"9000256027035"},{"@type":"NRID","@value":"9000257729281"},{"@type":"NRID","@value":"9000018877978"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0184017"}],"foaf:name":[{"@value":"Kiyotake Suenaga"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00404020"}],"prism:publicationName":[{"@value":"Tetrahedron"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2002-08-01","prism:volume":"58","prism:startingPage":"6405","prism:endingPage":"6412"},"dataSourceIdentifier":[{"@type":"OPENAIRE","@value":"doi_dedup___::06d32377f9f9c89026764456c1b2dac1"}]}