{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1882272492419187072.json","@type":"Dataset","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.5061/dryad.5dn13"}}],"dc:title":[{"@value":"Data from: Significant correlation between retinal venous tortuosity and aqueous vascular endothelial growth factor concentration in eyes with central retinal vein occlusion"}],"dc:language":"en","description":[{"notation":[{"@value":"Purpose: To determine whether the degree of venous tortuosity is  significantly correlated with the aqueous vascular endothelial growth  factor (VEGF) concentration in eyes with a central retinal vein occlusion  (CRVO). Methods: We reviewed the medical records of 32 eyes of 32 patients  who had macular edema due to a CRVO. All of the patients were examined at  the Nagoya University Hospital and were scheduled to receive an  intravitreal injection of bevacizumab (IVB) or ranibizumab (IVR) within 12  weeks of the onset of the CRVO to treat the macular edema. Aqueous humor  was collected just before the IVB or IVR, and the VEGF concentration was  determined by enzyme-linked immunosorbent assay (ELISA). The venous  tortuosity index was calculated by dividing the length of the retinal  veins by the chord length of the same segment. The correlation between the  mean tortuosity index of the inferotemporal and supratemporal branches of  the retinal vein and the aqueous VEGF concentration was determined.  Results: The mean aqueous VEGF concentration was 384 ± 312 pg/ml with a  range of 90 to 1077 pg/ml. The degree of venous tortuosity was  significantly correlated with the VEGF concentration in the aqueous. (r =  0.49, P = 0.004), with the foveal thickness (r = 0.40, P = 0.02), and with  the best-corrected visual acuity (r = 0.38, P = 0.03). Conclusions: The  significant correlation between the aqueous VEGF concentration and the  venous tortuosity indicates that the degree of retinal venous tortuosity  can be used to identify eyes that are at a high risk of developing  neovascularization."}]},{"notation":[{"@value":"CRVO tortuosity Data English"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1892272492419187075","@type":"Researcher","foaf:name":[{"@value":"Yasuda, Shunsuke"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492419187077","@type":"Researcher","foaf:name":[{"@value":"Kachi, Shu"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492419187072","@type":"Researcher","foaf:name":[{"@value":"Ueno, Shinji"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492419187074","@type":"Researcher","foaf:name":[{"@value":"Kondo, Mineo"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492419187073","@type":"Researcher","foaf:name":[{"@value":"Kaneko, Hiroki"}]},{"@id":"https://cir.nii.ac.jp/crid/1892272492419187076","@type":"Researcher","foaf:name":[{"@value":"Terasaki, Hiroko"}]}],"publication":{"dc:publisher":[{"@value":"Dryad"}],"prism:publicationDate":"2015-01-01"},"dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Visual%20acuity","dc:title":"Visual acuity"},{"@id":"https://cir.nii.ac.jp/all?q=Visual%20Acuity","dc:title":"Visual Acuity"},{"@id":"https://cir.nii.ac.jp/all?q=Life%20Sciences","dc:title":"Life Sciences"},{"@id":"https://cir.nii.ac.jp/all?q=eyes","dc:title":"eyes"},{"@id":"https://cir.nii.ac.jp/all?q=Retinal%20disorders","dc:title":"Retinal disorders"},{"@id":"https://cir.nii.ac.jp/all?q=Life%20sciences","dc:title":"Life sciences"},{"@id":"https://cir.nii.ac.jp/all?q=Veins","dc:title":"Veins"},{"@id":"https://cir.nii.ac.jp/all?q=medicine%20and%20health%20care","dc:title":"medicine and health care"},{"@id":"https://cir.nii.ac.jp/all?q=Vasculogenesis","dc:title":"Vasculogenesis"},{"@id":"https://cir.nii.ac.jp/all?q=Medicine","dc:title":"Medicine"},{"@id":"https://cir.nii.ac.jp/all?q=Edema","dc:title":"Edema"},{"@id":"https://cir.nii.ac.jp/all?q=Eyes","dc:title":"Eyes"},{"@id":"https://cir.nii.ac.jp/all?q=Enzyme-linked%20immunoassays","dc:title":"Enzyme-linked immunoassays"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360567187528361088","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isSupplementTo","isReferencedBy","references"],"jpcoar:relatedTitle":[{"@value":"Significant Correlation between Retinal Venous Tortuosity and Aqueous Vascular Endothelial Growth Factor Concentration in Eyes with Central Retinal Vein Occlusion"}]},{"@id":"https://cir.nii.ac.jp/crid/1881709542609670400","@type":"Dataset","relationType":["hasPart"],"jpcoar:relatedTitle":[{"@value":"CRVO tortuosity Data English"}]}],"dataSourceIdentifier":[{"@type":"OPENAIRE","@value":"doi_dedup___::58fbc1b1ea5497ecadb5372723b0c118"}]}