{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/2050870366997400448.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"NDL_BIB_ID","@value":"10691636"}},{"identifier":{"@type":"NAID","@value":"110002105946"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/digimeta/10691636"}},{"identifier":{"@type":"URI","@value":"https://dl.ndl.go.jp/pid/10691636"}},{"identifier":{"@type":"URI","@value":"http://dl.ndl.go.jp/info:ndljp/pid/10691636"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/1992141487"}}],"dc:title":[{"@value":"子宮頚癌予後判別におけるX線CTの役割"}],"dcterms:alternative":[{"@value":"子宮頚癌予後判別におけるX線CTの役割"},{"@value":"Role of X-ray Computed Tomography in the Evaluation of Prognosis of Cervical Carcinoma"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@value":"5年以上の転帰が判明している129例(転帰良好75例, 不良54例)を対象として, 子宮頚癌の治療前CT所見に基づく予後判別を試みた. CT所見の評価は当教室で使用している9項目の分類に従った. 1)良好群, 不良群別の各項目における所見出現率は各々, (1)子宮頚部陰影の拡大40.0%, 64.8%(p<0.01), (2)子宮頚部陰影内のlow density area 18.7%, 37.0%(p<0.05), (3)壊死性空洞4.0%, 33.3%(p<0.001), (4)子宮留膿症8.0%, 31.5%(p<0.01), (5)子宮頚部陰影の不整不明瞭2.7%, 51.9%(p<0.001), (6)子宮傍組織陰影25.3%, 87.0%(p<0.001), (7)腔方向への進展2.7%, 37.0%(p<0.001), (8)膀胱方向への進展8.0%, 57.4%(p<0.001), (9)リンパ節陰影の拡大0%, 27.8%(p<0.001)とすべての項目で不良群における所見出現率が有意に高かった. 2)数量化II類を用いて多変量解析を行ない, それをもとに以下のごとき予後判別CTスコアを作成した. 各項目の, 所見なし, (6)の陰影なし, type A, および(8)のgrade 0を0点とし, (1)+1, (2)-1, (3)+1, (1)-3, (5)+25, (6)type B+29, C+25, D+10, (7)+2, (8)grade I+12, II+7, III+20, (9)+18, の点数とし, 判別点を0とするために定数を-30とした. このスコアによる予後良好, 不良の判別率は, 82.9%であり, 放射線治療例(n=47)のみの検討では-2を判別点とした場合の判別率は85.1%であった. 3)進行期とCTスコアの点数の検討では, 期が進むに従い有意に点数が高くなり, 同一期内でも良好群, 不良群間の点数はII期, III期で有意差が認められた. 不良群における点数と生存月数の間には負の相関があり(r=-0.37, p<0.05), 放射線治療例ではさらに高い相関が認められた(r=-0.54, p<0.01). 以上の成績より, 今回作成したCTスコアは予後判別のみならず, 頚癌進行度の評価や再発のrisk推定にも有用であるとの結論を得た."},{"@value":"In 129 patients with cervical cancer, CT findings before treatment were analysed on the basis of the outcome during a 5 year follow-up period (75 survivals, and 54 deaths). 1) The incidence of each CT finding in the two groups was ; (1) enlargement of the uterine cervix : 40.0% in survivals, 64.8% in deaths, (2) low density area in the cervix : 18. 7%, 37.0%, (3) necrotic cavity : 4.0%, 33.3%, (4) pyometra : 8.0%, 31.5%, (5) irregular and indistinct margin of the cervix : 2. 7%, 51.9%, (6) abnormal image of parametrium : 25.3%, 87.0%, (7) extension to the vagina : 2.7%, 37.0%, (8) extension toward the bladder : 8.0%, 57.4%, and (9) enlarged lymph node : 0%, 27.8%. 2) CT scores obtained by multivariate analysis for prognostic discrimination of cervical cancer were (1)+1, (2)-1, (3)+1, (4)-3, (5)+25, (6) type B+29, C+25, D+10, O+2, (8) grade I+12, II+7, III+20, and (9)+18, respectively. The discrimination ratio for the prognosis of cervical cancer was 82.9%. 3) The score obtained by multivariate analysis showed significant increases according with the stage. Even in the same stage, there were significant differences between the scores for survivals and deaths (stage II : p<0.01, stage III : p<0.05). The survival period in the poor prognosis group was correlated with the score, especially in the cases treated with radiotherapy (r=-0.54, p<0.01)."}]},{"notation":[{"@value":"収集根拠 : NII-ELS"},{"@value":"資料形態 : テキストデータ"},{"@value":"コレクション : 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > 学術機関 > 学協会"},{"@value":"著者所属: 杏林大学医学部産科婦人科学教室"},{"@value":"Affiliation: Department of Obstetrics and Gynecology Kyorin University School of Medicine"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1580009752271048576","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000364132996"}],"foaf:name":[{"@value":"山田,榮子"}]}],"publication":{"publicationIdentifier":[{"@type":"NCID","@value":"AN00190060"}],"prism:publicationName":[{"@value":"日本産科婦人科學會雜誌"}],"dc:publisher":[{"@value":"日本産科婦人科学会"}],"prism:publicationDate":"1991-02-01","prism:volume":"43(2)","prism:startingPage":"205","prism:endingPage":"212"},"url":[{"@id":"http://id.ndl.go.jp/digimeta/10691636"},{"@id":"https://dl.ndl.go.jp/pid/10691636"},{"@id":"http://dl.ndl.go.jp/info:ndljp/pid/10691636"},{"@id":"https://search.jamas.or.jp/link/ui/1992141487"}],"foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Computed%20tomography%20(CT)","dc:title":"Computed tomography (CT)"},{"@id":"https://cir.nii.ac.jp/all?q=Cervical%20carcinoma","dc:title":"Cervical carcinoma"},{"@id":"https://cir.nii.ac.jp/all?q=Prognostic%20score","dc:title":"Prognostic score"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/2050870367000888576","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@value":"子宮頸癌による子宮留膿腫のため自然子宮穿孔をきたした2例"}]}],"dataSourceIdentifier":[{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R100000039-I10691636"},{"@type":"NDL_DC","@value":"info:ndljp/pid/10691636"},{"@type":"CIA","@value":"110002105946"}]}