{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/2051996266964363904.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"NDL_BIB_ID","@value":"11085514"}},{"identifier":{"@type":"NAID","@value":"110003994261"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/digimeta/11085514"}},{"identifier":{"@type":"URI","@value":"https://dl.ndl.go.jp/pid/11085514"}},{"identifier":{"@type":"URI","@value":"http://dl.ndl.go.jp/info:ndljp/pid/11085514"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2005287125"}}],"dc:title":[{"@value":"Extracellular Matrix Formed by MC3T3-E1 Osteoblast-Like Cells Cultured on Titanium : I. Anchor Structure"}],"dcterms:alternative":[{"@value":"Extracellular Matrix Formed by MC3T3-E1 Osteoblast-Like Cells Cultured on Titanium : I. Anchor Structure"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@value":"In order to clarify the structure of the extracellular matrix formed by osteoblasts in contact with titanium, we analyzed the structure formed by cultured clonal MC3T3-E1 osteoblasts on a calcified surface of commercial pure titanium, after exfoliating the cells from the surface of the titanium. Collagen fibers formed between neighboring cells and between cells and titanium, in the latter case with one tip of each collagen fiber bound to the cell and the other tip bound to the surface of the titanium embedded in the calcified layer. We called this structure an \"anchor structure\", because the collagen fibers embedded in the calcified layer anchor the cells to the titanium. This structure may be a reason for the useful biocompatibility between titanium and bone."}]},{"notation":[{"@value":"収集根拠 : NII-ELS"},{"@value":"資料形態 : テキストデータ"},{"@value":"コレクション : 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > 学術機関 > 学協会"},{"@value":"著者所属: Department of Anatomy, School of Dentistry, University of Tokushima"},{"@value":"著者所属: Department of Dental Anesthesiology, School of Dentistry, University of Tokushima"},{"@value":"著者所属: Biomaterial Center, National Institute for Materials Science"},{"@value":"著者所属: Department of Removable Prosthodontics, School of Dentistry, University of Tokushima"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1030003658324122112","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"30182497"},{"@type":"NRID","@value":"1000030182497"},{"@type":"NRID","@value":"9000002725850"},{"@type":"NRID","@value":"9000391828464"},{"@type":"NRID","@value":"9000266428233"},{"@type":"NRID","@value":"9000253266496"},{"@type":"NRID","@value":"9000254852755"},{"@type":"NRID","@value":"9000345303945"},{"@type":"NRID","@value":"9000254852982"},{"@type":"NRID","@value":"9000020317620"},{"@type":"NRID","@value":"9000004734374"},{"@type":"NRID","@value":"9000257963656"},{"@type":"NRID","@value":"9000001842341"},{"@type":"NRID","@value":"9000006637024"},{"@type":"NRID","@value":"9000387917811"},{"@type":"NRID","@value":"9000391824668"},{"@type":"NRID","@value":"9000257963940"},{"@type":"NRID","@value":"9000257899964"},{"@type":"NRID","@value":"9000329899551"},{"@type":"NRID","@value":"9000254852095"},{"@type":"NRID","@value":"9000020663543"},{"@type":"NRID","@value":"9000391823796"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0017447"}],"foaf:name":[{"@value":"YAMASHITA,Kikuji"}]},{"@id":"https://cir.nii.ac.jp/crid/1582261552230531845","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000005793439"}],"foaf:name":[{"@value":"EGUCHI,Satoru"}]},{"@id":"https://cir.nii.ac.jp/crid/1580291225302089351","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000002725860"}],"foaf:name":[{"@value":"MORIMOTO,Hiroyuki"}]},{"@id":"https://cir.nii.ac.jp/crid/1582261552230531841","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000005793445"}],"foaf:name":[{"@value":"HANAWA,Takao"}]},{"@id":"https://cir.nii.ac.jp/crid/1582261552230531842","@type":"Researcher","foaf:name":[{"@value":"ICHIKAWA,Tetsuo"}]},{"@id":"https://cir.nii.ac.jp/crid/1030003658379960577","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"80069046"},{"@type":"NRID","@value":"1000080069046"},{"@type":"NRID","@value":"9000000675380"},{"@type":"NRID","@value":"9000021090614"},{"@type":"NRID","@value":"9000008691397"},{"@type":"NRID","@value":"9000010235020"},{"@type":"NRID","@value":"9000254051565"},{"@type":"NRID","@value":"9000005793453"},{"@type":"NRID","@value":"9000256884949"},{"@type":"NRID","@value":"9000000534012"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0017494"}],"foaf:name":[{"@value":"NAKAJO,Nobuyoshi"}]},{"@id":"https://cir.nii.ac.jp/crid/1582261552230531844","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000002725862"}],"foaf:name":[{"@value":"KITAMURA,Seiichiro"}]}],"publication":{"publicationIdentifier":[{"@type":"NCID","@value":"AN10169901"}],"prism:publicationName":[{"@value":"Connective tissue"}],"dc:publisher":[{"@value":"日本結合組織学会"}],"prism:publicationDate":"2004-04-08","prism:volume":"36(1)","prism:startingPage":"1","prism:endingPage":"8"},"url":[{"@id":"http://id.ndl.go.jp/digimeta/11085514"},{"@id":"https://dl.ndl.go.jp/pid/11085514"},{"@id":"http://dl.ndl.go.jp/info:ndljp/pid/11085514"},{"@id":"https://search.jamas.or.jp/link/ui/2005287125"}],"foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=MC3T3-E1","dc:title":"MC3T3-E1"},{"@id":"https://cir.nii.ac.jp/all?q=extracellular%20matrix","dc:title":"extracellular matrix"},{"@id":"https://cir.nii.ac.jp/all?q=titanium","dc:title":"titanium"},{"@id":"https://cir.nii.ac.jp/all?q=type%20I%20collagen","dc:title":"type I collagen"},{"@id":"https://cir.nii.ac.jp/all?q=anchor%20structure","dc:title":"anchor structure"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011144319576832","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"The bone–titanium interface<i>in vitro</i>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011145842414976","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"Apatite deposition on titanium surfaces — the role of albumin adsorption"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893970141568","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"Treatment of Peri‐Implant Defects With Combination Growth Factor Cement"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825895361893248","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"The structure of interfibrillar proteoglycan bridges (‘shape modules’) in extracellular matrix of fibrous connective tissues and their stability in various chemical environments"}]},{"@id":"https://cir.nii.ac.jp/crid/1570009750196660864","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Quasi-biological apatite film induced by titanium in a simulated body fluid"}]},{"@id":"https://cir.nii.ac.jp/crid/1570291225173180032","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Tissue reactions to titanium implants containing bovine bone morphogenetic protein : a scanning electron microscopic investigation"}]},{"@id":"https://cir.nii.ac.jp/crid/1570291225173371520","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Characterization of surface film formed on titanium in electrolyte using XPS"}]},{"@id":"https://cir.nii.ac.jp/crid/1570572699081069952","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Isolation and partial characterization of collagen fibers and fiber-bundles from insoluble calf dermis"}]},{"@id":"https://cir.nii.ac.jp/crid/1570572699163287552","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Light and electron microscopic studies of bone-titanium interface in the tibiae of young and mature rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1570572699370372352","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Further characterization of interaction between bone sialoprotein (BSP) and collagen"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854175126602624","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Deposition of cement-like matrix on implant materials"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854176696783360","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Surface analysis of titanium implants"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854176698116864","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Examination of osteoblast-orthopedic biomaterial interactions using molecular techniques"}]},{"@id":"https://cir.nii.ac.jp/crid/1571417125080022272","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Modulation of growth factor incorporation into ECM of human osteoblast-like cells in vitro by 17β-estradiol"}]},{"@id":"https://cir.nii.ac.jp/crid/1571417126720483072","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"FT-IR study for hydroxyapatite/collagen nanocomposite cross-linked by glutaraldehyde"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698599990403840","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The effect of alkali- and heat-treated titanium and apatite-formed titanium on osteoblastic differentiation of bone marrow cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698600056928128","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A histological investigation on tissue responses to titanium implants in cortical bone of the rat femur"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980075033445632","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Surface modification of poly (ethylene-co-vinyl alcohol) (EVA). Part I. Introduction of carboxyl groups and immobilization of collagen"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980076645048576","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Collagen type I-coating of Ti6Al4V promotes adhesion of osteoblasts"}]},{"@id":"https://cir.nii.ac.jp/crid/1572261551365574272","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Immobilization of glucoamylase on gelatin by transition-metal chelation"}]},{"@id":"https://cir.nii.ac.jp/crid/1572261551606879232","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Structure of surface-modified layers of calcium-ionimplanted Ti-6 Al-4 V and Ti-56 Ni"}]},{"@id":"https://cir.nii.ac.jp/crid/1572543024986865024","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Bone cell behavior on Matrigel-coated Ca/P coatings of varying crystallinities"}]},{"@id":"https://cir.nii.ac.jp/crid/1572824499963577344","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Cranioplasty performed with a new osteoconductive, osteoinducing hydroxyapatite-derived material"}]},{"@id":"https://cir.nii.ac.jp/crid/1573105974940288512","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Optimal methods for processing mineralized tissues for Fourier transform infrared microspectroscopy"}]},{"@id":"https://cir.nii.ac.jp/crid/1574231874847130752","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effect of Heat Treatment on Apatite-forming Ability of Ti Metal Induced by Alkali Treatment"}]},{"@id":"https://cir.nii.ac.jp/crid/1574231875816437760","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Fibrous-long spacing fiber formation by collagen and non-collagenous acidic components from calf skin"}]}],"dataSourceIdentifier":[{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R100000039-I11085514"},{"@type":"NDL_DC","@value":"info:ndljp/pid/11085514"},{"@type":"CIA","@value":"110003994261"}]}