【2022年1月締切】CiNii ArticlesへのCiNii Researchへの統合に伴う機関認証の移行確認について

【1/6更新】2022年4月1日からのCiNii ArticlesのCiNii Researchへの統合について

Lesions of supramammillary nucleus decreae self-grooming behavior of rats placed in an open field

この論文をさがす

抄録

type:Article

Aim : Although subcortical regions send numerous efferent fibers to the hippocampus, their involvement in hippocampal functions has not been fu11y elucidated. The aim of this study was to determine the efTect of the supram ammillary nucleus (SuM) on the hippocampus. Methods : Neurons within the SuM of rats were destroyed by local injections of an excitotoxin, ibotenic acid, and the efTects of the SuM-lesion on behaviors in an open field were investigated. Results: SuM lesions increased distance traveled, movement time and latency to start grooming, while they decreased time spent grooming. SuM lesions had no efTect on rearing frequency or immobility time. Conclusion : Prolonged exploration and decrease in the total time spent grooming observed in the SuM-lesioned rats were consistent with the beh avi oral characteri stics of hippocamp al -lesioned rats of the previ ous report s, suggesting that the SuM is involved in the establishment of spatial memory by hippocampus during the initial exploration of a novel environment. In addition, the reduction of grooming in the SuM-lesioned animal suggests that SuM may be involved in emotion, such as anxiety. The results ofthis study show the involvement ofthe SuM in hippocampal function and in anxiety perceived in anovel environment.

identifier:The Kitakanto medical journal. 61(3), 287-292, 2011

identifier:1343-2826

identifier:https://gair.media.gunma-u.ac.jp/dspace/handle/10087/6188

identifier:The Kitakanto medical journal, 61(3): 287-292

収録刊行物

被引用文献 (0)*注記

もっと見る

参考文献 (0)*注記

もっと見る

関連論文

もっと見る

関連研究データ

もっと見る

関連図書・雑誌

もっと見る

関連博士論文

もっと見る

関連プロジェクト

もっと見る

関連その他成果物

もっと見る

詳細情報

ページトップへ