【7/12更新】2022年4月1日からのCiNii ArticlesのCiNii Researchへの統合について

Comparison of Functional Outcomes of Patients Who Underwent Hand-Sewn or Stapled Ileal Pouch-Anal Anastomosis for Ulcerative Colitis

  • Hiroaki Ishii
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Kazushige Kawai
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Keisuke Hata
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Yasutaka Shuno
    Department of Surgery, Chigasaki Municipal Hospital, Tokyo, Japan
  • Takeshi Nishikawa
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Toshiaki Tanaka
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Junichiro Tanaka
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Tomomichi Kiyomatsu
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Hiroaki Nozawa
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Shinsuke Kazama
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Hironori Yamaguchi
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Soichiro Ishihara
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Eiji Sunami
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Joji Kitayama
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
  • Toshiaki Watanabe
    Department of Surgical Oncology, Faculty of Medicine, the University of Tokyo, Tokyo, Japan

抄録

<jats:p>Total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the standard surgical treatment for patients with ulcerative colitis (UC). The purpose of this study was to investigate the long-term functional outcomes and quality of life (QOL) associated with hand-sewn and stapled IPAA. Ninety-one patients with UC had undergone IPAA using hand-sewn anastomosis with mucosectomy (32 patients) or stapled anastomosis (59 patients) from January 1988 to May 2010. Patients were evaluated according to patient characteristics, postoperative complications, functional outcomes and QOL. The QOL of patients were evaluated using the Medical Outcomes Study Short Form 36 (SF-36) and the Inflammatory Bowel Disease Questionnaire (IBDQ). Numbers of patients with colorectal cancer or dysplasia were significantly greater in the hand-sewn IPAA group (P &lt; 0.01). These patients had longer disease durations and were older (both P &lt; 0.01). There was no difference in the incidence of complications between the groups, except for a greater incidence of postoperative anal fistula in the stapled group (P = 0.03). In the early postsurgery period, both the frequency of bowel movements and the rate of soiling were significantly higher in the hand-sewn group, but in a later period, there was no difference in these events &gt;3 years after surgery. The SF-36 and IBDQ results were similar in the two groups, indicating that hand-sewn and stapled IPAA result in similar QOL in the late postoperative period. Postoperative complications, functional outcomes, and long-term QOL were similar in patients who had received hand-sewn or stapled IPAA.</jats:p>

収録刊行物

  • International Surgery

    International Surgery 100 (7-8), 1169-1176, 2015-11-01

    International College of Surgeons

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