Development and application of next generation metabolome analysis technologies
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- Takeshi Bamba
- Principal Investigator
- 九州大学
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- 山田 健一
- Co-Investigator
- 九州大学
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- 和泉 自泰
- Co-Investigator
- 九州大学
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- 相馬 悠希
- Co-Investigator
- 九州大学
About this project
- Japan Grant Number
- JP17H06304
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding organization
- Japan Society for the Promotion of Science
- Project/Area Number
- 17H06304
- Research Category
- Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Allocation Type
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- Single-year Grants
- Review Section / Research Field
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- Biological Sciences
- Research Institution
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- Kyushu University
- Project Period (FY)
- 2017-06-30 〜 2022-03-31
- Project Status
- Completed
- Budget Amount*help
- 162,240,000 Yen (Direct Cost: 124,800,000 Yen Indirect Cost: 37,440,000 Yen)
Research Abstract
We have been working on the development of next-generation metabolome analysis base technologies that enables quantitative metabolome analysis and contributes to metabolic adaptation analysis. We succeeded in developing a quantitative metabolome analysis system using various chromatography-mass spectrometry systems. We also developed a system for quantitative analysis of individual components by combining LC and various detectors. In addition, we developed stable isotope-labeled internal standards necessary for quantitative analysis in mass spectrometry, probes for highly sensitive quantitative analysis of trace components, and a data analysis system for quantitative metabolome analysis. We have established the basic technologies for quantitative metabolome analysis, and have conducted many applied studies of metabolic adaptation using these technologies with collaborators both inside and outside of the project.
Keywords
Details 詳細情報について
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- CRID
- 1040000781959526144
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- Text Lang
- ja
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- Data Source
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- KAKEN
- IRDB