Amide proton transfer (APT) imaging of breast tumors
About this project
- Japan Grant Number
- JP18K07717
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding organization
- Japan Society for the Promotion of Science
- Project/Area Number
- 18K07717
- Research Category
- Grant-in-Aid for Scientific Research (C)
- Allocation Type
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- Multi-year Fund
- Review Section / Research Field
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- Basic Section 52040:Radiological sciences-related
- Research Institution
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- Kyushu University
- Project Period (FY)
- 2018-04-01 〜 2023-03-31
- Project Status
- Completed
- Budget Amount*help
- 4,420,000 Yen (Direct Cost: 3,400,000 Yen Indirect Cost: 1,020,000 Yen)
Research Abstract
We assessed the usefulness of APT imaging to predict the biological status of breast cancers. The triple-negative (TN) cancers showed significantly higher APT signal intensity (SI) than the luminal type cancers and HER2 cancers. APT SI had weakly positive correlation with the Ki-67 labeling index. The mean APT SIs were significantly higher for high-Ki-67 (>30%) than low-Ki-67 (≦30%) cancers. There was no significant difference in the APT SIs among nuclear grades. These results were presented at European Congress of Radiology 2022 and a paper was published in Clinical Imaging.
Details 詳細情報について
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- CRID
- 1040000782000305920
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- Text Lang
- ja
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- Data Source
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- KAKEN