Investigation pf a novel sterilisation method by peroxynitric acid for peri-implant infection
About This Project
- Japan Grant Number
- JP18K09685 (JGN)
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding Organization
- Japan Society for the Promotion of Science
Kakenhi Information
- Project/Area Number
- 18K09685
- Research Category
- Grant-in-Aid for Scientific Research (C)
- Allocation Type
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- Multi-year Fund
- Review Section / Research Field
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- Basic Section 57050:Prosthodontics-related
- Research Institution
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- Kyushu University
- Project Period (FY)
- 2018-04-01 〜 2022-03-31
- Project Status
- Completed
- Budget Amount*help
- 4,290,000 Yen (Direct Cost: 3,300,000 Yen Indirect Cost: 990,000 Yen)
Research Abstract
This research evaluated the bactericidal effects of peroxynitric acid (HOONO2; PNA) on biofilms formed on titanium surfaces. Streptococcus gordonii was cultured on titanium discs that were then used to evaluate the bactericidal effects of PNA. Using low concentration of PNA, the bacterial count based on a CFU assay reached an undetectable level within 10 s.Bacillus subtilis solution was coated on the dental model, and impression taking of the model was done by dental impression material. Dental impression material was disinfected by PNA, and bactericidal effects were evaluated. The bacterial count based on a CFU assay reached an undetectable level within 10 minutes. PNA is useful for sterilizing biofilms on titanium surfaces and dental impression material that have been contaminated with bacteria.
Details 詳細情報について
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- CRID
- 1040000782001449856
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- Text Lang
- ja
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- Data Source
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- KAKEN