A new high altitude adaptation model constructed from whole genome analysis and physiological information

About this project

Japan Grant Number
JP18K14808
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
18K14808
Research Category
Grant-in-Aid for Early-Career Scientists
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Basic Section 45060:Applied anthropology-related
Research Institution
  • Kyushu University
  • Nagasaki University
Project Period (FY)
2018-04-01 〜 2022-03-31
Project Status
Completed
Budget Amount*help
4,030,000 Yen (Direct Cost: 3,100,000 Yen Indirect Cost: 930,000 Yen)

Research Abstract

High-altitude adaptation studies have focused on low-hemoglobin-type adaptation by specific mutations in the EPAS1 gene in the Tibetan population, but few studies have focused on diversity within the population. Therefore, in this study, we performed physiological measurements of Tibetan and Andean populations by field research, and clarified various factors (gender, age, genetic background) related to their physiological variations.

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