Pharmacokinetic analysis of tumors in the maxillofacial region using Dual Energy CT

KAKEN

About This Project

Japan Grant Number
JP18K17170 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
18K17170
Research Category
Grant-in-Aid for Early-Career Scientists
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Basic Section 57060:Surgical dentistry-related
Research Institution
  • Kyushu University
Project Period (FY)
2018-04-01 〜 2022-03-31
Project Status
Completed
Budget Amount*help
4,030,000 Yen (Direct Cost: 3,100,000 Yen Indirect Cost: 930,000 Yen)

Research Abstract

We established a Dual Energy CT (DECT) protocol in the maxillofacial region and investigated whether parameters calculated from DECT images are effective in the diagnosis of metastatic lymph nodes of squamous cell carcinoma. Cervical lymph nodes larger than 5 mm were included in the study to determine the variation in CT values at 40, 70, and 100 keV and iodine content within the lymph nodes, and to correlate them with pathology. Metastatic lymph nodes tended to have significantly smaller contrast uptake than non-metastatic nodes, suggesting that DECT is likely to be associated with pathological changes within metastatic lymph nodes.

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