Continuum biomechanics of the whole brain circulation for the computational analysis of cerebrovascular diseases

About this project

Japan Grant Number
JP19H01175
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
19H01175
Research Category
Grant-in-Aid for Scientific Research (A)
Allocation Type
  • Single-year Grants
Review Section / Research Field
  • Medium-sized Section 90:Biomedical engineering and related fields
Research Institution
  • Osaka University
Project Period (FY)
2019-04-01 〜 2023-03-31
Project Status
Completed
Budget Amount*help
45,500,000 Yen (Direct Cost: 35,000,000 Yen Indirect Cost: 10,500,000 Yen)

Research Abstract

臓器の形態と解剖学的構造,流体と構造の連成,構成要素の階層性や応答など,生体特有の複雑な力学的特性を考慮した連続体力学に基づいて,全脳の血液循環,脳組織の変形と細胞間質液の流動,脳神経活動に必要な酸素と代謝基質の輸送,老廃物の排出を担う脳脊髄液の循環の時空間場における物理的連立関係を数値シミュレーションにより明らかにする.これにより,正常な脳機能が維持されるための全脳循環代謝動態とそれを引き起こすメカニズムを解明し,力学的平衡状態を崩す脳出血や脳梗塞などの脳血管障害において,医用画像で観察される現象や病態を物理的側面から分析する.

Related Articles

See more

Related Data

See more

Related Books

See more

Related Dissertations

See more

Related Projects

See more

Related Products

See more
Back to top