Modulation of mRNA splicing for the genetic diseases

About this project

Japan Grant Number
JP21591365
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
21591365
Research Category
Grant-in-Aid for Scientific Research (C)
Allocation Type
  • Single-year Grants
Review Section / Research Field
  • Biological Sciences > Medicine, Dentistry, and Pharmacy > Clinical internal medicine > Pediatrics
Research Institution
  • Kawasaki Medical School
Project Period (FY)
2009 〜 2011
Project Status
Completed
Budget Amount*help
4,420,000 Yen (Direct Cost: 3,400,000 Yen Indirect Cost: 1,020,000 Yen)

Research Abstract

The gaol of this research is an analysis of transcription, post-transcription and the modulation of mRNA. This researches clarified transcriptional regulation of the phagocyte NADPH oxidase(J. Immunol. 2011, BBRC 2010) and signal transduction by oxidative stress for the cells(BBRC 2011). This reaearch further developed the method to detect superoxide quantitatively(Tropical Medicine and Health. 2011).

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