Innovative Therapies Targeting Increased Susceptibility to Chemoradiotherapy for Esophageal Cancer
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- Nakashima Yuichirou
- Principal Investigator
- 独立行政法人国立病院機構(九州がんセンター臨床研究センター)
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- 安藤 幸滋
- Co-Investigator
- 九州大学
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- 沖 英次
- Co-Investigator
- 九州大学
About This Project
- Japan Grant Number
- JP20K09105 (JGN)
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding Organization
- Japan Society for the Promotion of Science
Kakenhi Information
- Project/Area Number
- 20K09105
- Research Category
- Grant-in-Aid for Scientific Research (C)
- Allocation Type
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- Multi-year Fund
- Review Section / Research Field
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- Basic Section 55020:Digestive surgery-related
- Research Institution
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- National Hospital Organization, Kyushu Cancer Center
- Project Period (FY)
- 2020-04-01 〜 2023-03-31
- Project Status
- Completed
- Budget Amount*help
- 4,290,000 Yen (Direct Cost: 3,300,000 Yen Indirect Cost: 990,000 Yen)
Research Abstract
食道扁平上皮癌の化学放射線療法感受性に関与する相互組換え修復の主要因子であるRad51発現を調節するE2F1/Rb-CDK4/6/Cyclin D1経路に着目し、CDK4/6阻害薬による化学放射線療法の感受性の改善効果を検討する。
Keywords
Details 詳細情報について
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- CRID
- 1040003825725000192
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- Text Lang
- ja
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- Data Source
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- KAKEN