生体活性人工血管の開発と血管組織修復のための免疫調節の役割の解明

KAKEN

About This Project

Japan Grant Number
JP22KF0287 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
22KF0287
Research Category
Grant-in-Aid for JSPS Fellows
Allocation Type
  • Multi-year Fund
  • Single-year Grants
Review Section / Research Field
  • Basic Section 27040:Biofunction and bioprocess engineering-related
Research Institution
  • Kyushu University
Project Period (FY)
2023-03-08 〜 2024-03-31
Project Status
Completed
Budget Amount*help
2,200,000 Yen (Direct Cost: 2,200,000 Yen Indirect Cost: 0 Yen)

Research Abstract

The aim of this research is to decipher the role of immunomodulation for engineering synthetic vascular grafts, which will be accomplished by exploiting decellularized extracellular matrix (dECM) and different immunomodulatory cues. Cell free vascular grafts may offer an invaluable platform for vascular tissue engineering. In this study, PLCL / dECM based hybrid vascular grafts will be developed by electrospinning. Furthermore, immobilize bioactive cues will elucidate the role of immunomodulatory for vascular tissue repair.

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