Analysis of PTPN3-LCN2-TK phosphorylation pathway in HNSCC

About this project

Japan Grant Number
JP24K12718
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
24K12718
Research Category
Grant-in-Aid for Scientific Research (C)
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Basic Section 56050:Otorhinolaryngology-related
Research Institution
  • Kyushu University
Project Period (FY)
2024-04-01 〜 2027-03-31
Project Status
Granted
Budget Amount*help
4,680,000 Yen (Direct Cost: 3,600,000 Yen Indirect Cost: 1,080,000 Yen)

Research Abstract

我々が見出した、頭頚部扁平上皮癌(HNSCC)において認められるprotein tyrosine phosphatase non-receptor type 3(PTPN3)-Lipocalin 2(LCN2)-チロシンキナーゼ(TK)リン酸化経路(PTPN3-LCN2-TKリン酸化経路)の分子生物学的解析を行い、HNSCCの病態解析を行うとともに、HNSCCの新規治療法を開発する。

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