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Analysis of PTPN3-CACNA1G-TK phosphorylation pathway in lung NET
About This Project
- Japan Grant Number
- JP23K24422 (JGN)
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding Organization
- Japan Society for the Promotion of Science
Kakenhi Information
- Project/Area Number
- 23K24422
- Research Category
- Grant-in-Aid for Scientific Research (B)
- Allocation Type
-
- Multi-year Fund
- Single-year Grants
- Review Section / Research Field
-
- Basic Section 55040:Respiratory surgery-related
- Research Institution
-
- Kyushu University
- Project Period (FY)
- 2022-04-01 〜 2025-03-31
- Project Status
- Granted
- Budget Amount*help
- 17,420,000 Yen (Direct Cost: 13,400,000 Yen Indirect Cost: 4,020,000 Yen)
Research Abstract
我々が先の研究で新たに見出した、肺神経内分泌腫瘍（肺NET）に存在するprotein tyrosine phosphatase non-receptor type 3(PTPN3)ーカルシウムイオンチャネル：calcium voltage-gated channel subunit alpha 1G (CACNA1G)ーチロシンキナーゼ（TK）リン酸化経路(PTPN3-CACNA1G-TKリン酸化経路)の解析を行い、肺NETの病態解析を行うとともに、新規治療法を開発する。