Elucidation of the role of gut microbiota in promoting health and longevity

About this project

Japan Grant Number
JP23K27654
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
23K27654
Research Category
Grant-in-Aid for Scientific Research (B)
Allocation Type
  • Multi-year Fund
  • Single-year Grants
Review Section / Research Field
  • Basic Section 54040:Metabolism and endocrinology-related
Research Institution
  • Kyushu University
  • Keio University
Project Period (FY)
2023-04-01 〜 2027-03-31
Project Status
Granted
Budget Amount*help
18,460,000 Yen (Direct Cost: 14,200,000 Yen Indirect Cost: 4,260,000 Yen)

Research Abstract

百寿者の便中に特異的に存在していた二次胆汁酸の宿主への作用について受容体の同定、シグナル伝達経路の解明を行う。同時に、百寿者由来腸内細菌株を使用して、腸内細菌による新規コレステロールやステロイドホルモンの代謝経路の解明を行い、腸内細菌を用いた疾患予防法の開発および健康長寿社会の実現につなげることを目的として研究を行う。

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