Small-diameter vessels of human adipose stem cells by bio 3D printer

About this project

Japan Grant Number
JP17K17020
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
17K17020
Research Category
Grant-in-Aid for Young Scientists (B)
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Biological Sciences > Medicine, Dentistry, and Pharmacy > Clinical surgery > Plastic surgery
Research Institution
  • Kyushu University
Project Period (FY)
2017-04-01 〜 2022-03-31
Project Status
Completed
Budget Amount*help
2,600,000 Yen (Direct Cost: 2,000,000 Yen Indirect Cost: 600,000 Yen)

Research Abstract

Regarding the creation of small-diameter artificial vessels using adipose stem cells using a 3D printer, the investigator was working at a hospital other than the university, and there were restrictions due to COVID-19, making it difficult to use the animal research facility. Several cases of regenerated vascular grafts were performed in rats, but the development of vessels was not reached. As an alternative to the above study, we actively performed preoperative simulations of tissue reconstruction of the skull, jaw, and limb bones using a 3D printer. These findings are reported in three conference presentations and two articles. Regarding clinical application, it was pre-examined by the ARO (Center for Advanced Medicine and Clinical Research of Kyushu University) as "intervention study of the usefulness of computer-aided manufacturing in the reconstruction and formation of skull and maxillofacial bone", but it was withdrawn because the examination cost exceeded the research budget.

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