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About this project

Japan Grant Number
JP18H02914
Funding Program
Grants-in-Aid for Scientific Research
Funding organization
Japan Society for the Promotion of Science
Project/Area Number
18H02914
Research Category
Grant-in-Aid for Scientific Research (B)
Allocation Type
  • Single-year Grants
Review Section / Research Field
  • Basic Section 56010:Neurosurgery-related
Research Institution
  • National Cardiovascular Center Research Institute
  • Kyushu University
Project Period (FY)
2018-04-01 〜 2022-03-31
Project Status
Completed
Budget Amount*help
17,420,000 Yen (Direct Cost: 13,400,000 Yen Indirect Cost: 4,020,000 Yen)

Research Abstract

The goals of this study were to develop a new prediction model to predict long-term poor prognosis (recurrent stroke within 1/3/5 years) in patients with acute ischemic stroke and to compare the performance of the new prediction model with other classic prediction scales. Machine learning algorithms were applied to train predictive models for estimating the individual risk of recurrent stroke with medical information 105 variables contained in DPC data for 597,134 patients enrolled in the J-ASPECT Study in the 2010-19 period. The prediction accuracy of the recurrence prediction model within 1/3/5 years was 0.62/0.62/0.63, which exceeded the prediction accuracy by classical risk scores. The prediction accuracy was sustained using 16 items including age, gender, medical history, smoking history, rehabilitation and appropriate secondary prevention at discharge, hospital stay, ADL at discharge and discharge location (0.61/0.62/0.62).

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