Fabrication of osteoconductive polyethylene terephtharate
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- Ishikawa Kunio
- Principal Investigator
- 九州大学
About this project
- Japan Grant Number
- JP18K19928
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding organization
- Japan Society for the Promotion of Science
- Project/Area Number
- 18K19928
- Research Category
- Grant-in-Aid for Challenging Research (Exploratory)
- Allocation Type
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- Multi-year Fund
- Review Section / Research Field
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- Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
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- Kyushu University
- Project Period (FY)
- 2018-06-29 〜 2023-03-31
- Project Status
- Completed
- Budget Amount*help
- 6,370,000 Yen (Direct Cost: 4,900,000 Yen Indirect Cost: 1,470,000 Yen)
Research Abstract
Polyethylene terephthalate has been used as an artificial tendon and an artificial ligament. However, polyethylene terephthalate has no bone-bonding ability. In this study, we tried to give a function of bone bonding to polyethylene terephthalate to change the surface properties of polyethylene terephthalate. In this study, we prepared two types of polyethylene terephthalate, surface hydrolyzed polyethylene terephthalate and phosphate modified polyethylene terephthalate. Compared with non-treated polyethylene terephthalate, surface treated polyethylene terephthalate improved the osteoblast activity and bone bonding ability in vivo experiment. Thus, we reveal that the surface treatment could give a bone bonding ability to polyethylene terephthalate.
Details 詳細情報について
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- CRID
- 1040282256983137664
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- Text Lang
- ja
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- Data Source
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- KAKEN