Clinical application of heart rate variability for child-onset neuromuscular diseases

About This Project

Japan Grant Number
JP25860877 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
25860877
Research Category
Grant-in-Aid for Young Scientists (B)
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Biological Sciences > Medicine, Dentistry, and Pharmacy > Clinical internal medicine > Pediatrics
Research Institution
  • Nagoya City University
Project Period (FY)
2013-04-01 〜 2017-03-31
Project Status
Completed
Budget Amount*help
4,420,000 Yen (Direct Cost: 3,400,000 Yen Indirect Cost: 1,020,000 Yen)

Research Abstract

The goal of this study is to find prognostic factors of neuromuscular disease, using heart rate variability. Here we investigated the relation between heart rate variability and mortality of Duchenne muscular dystrophy. We analyzed 77 24-hour holter ECG data of15 patients who died. Each parameters of heart rate variability was depressed nearing to death, statistically significant. But there were no significant correlations between arrhythmia and mortality. These results was similar to previous reports of myocardial infarction. Heart rate variability was suggested to predict the prognosis of patients with neuromuscular diseases.

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