免疫微小環境を標的とした高悪性度肝細胞癌に対する統合的治療戦略の開発
About this project
- Japan Grant Number
- JP23K08222
- Funding Program
- Grants-in-Aid for Scientific Research
- Funding organization
- Japan Society for the Promotion of Science
- Project/Area Number
- 23K08222
- Research Category
- Grant-in-Aid for Scientific Research (C)
- Allocation Type
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- Multi-year Fund
- Review Section / Research Field
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- Basic Section 55020:Digestive surgery-related
- Research Institution
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- Jikei University School of Medicine
- Project Period (FY)
- 2023-04-01 〜 2026-03-31
- Project Status
- Granted
- Budget Amount*help
- 4,810,000 Yen (Direct Cost: 3,700,000 Yen Indirect Cost: 1,110,000 Yen)
Research Abstract
TP53-KO＋MYC-OE高悪性度肝細胞癌株を免疫学的活性正常同種マウスに移植、その細胞学的特性および癌周囲微小免疫環境の変化を分子生物学的に明らかにし、高悪性度肝細胞癌に対する新たな革新的治療戦略を確立する。
Details 詳細情報について
-
- CRID
- 1040295802073923072
-
- Text Lang
- ja
-
- Data Source
-
- KAKEN