Development of a novel oral vaccine for fish: Synergy of chitosan nano particle and complement-mediated opsonization

KAKEN

About This Project

Japan Grant Number
JP24K17960 (JGN)
Funding Program
Grants-in-Aid for Scientific Research
Funding Organization
Japan Society for the Promotion of Science

Kakenhi Information

Project/Area Number
24K17960
Research Category
Grant-in-Aid for Early-Career Scientists
Allocation Type
  • Multi-year Fund
Review Section / Research Field
  • Basic Section 40040:Aquatic life science-related
Research Institution
  • Kyushu University
Project Period (FY)
2024-04-01 〜 2027-03-31
Project Status
Granted
Budget Amount*help
4,680,000 Yen (Direct Cost: 3,600,000 Yen Indirect Cost: 1,080,000 Yen)

Research Abstract

The current study proposes utilizing chitosan nanoparticle tagged with the complement protein C3b as a drug delivery vehicle for oral fish vaccines. The encapsulation of the vaccine in chitosan nanoparticle protects the antigen from getting degraded and C3b enhances the opsonization of the vaccine.

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